Objective:To investigate the expression of tumor necrosis factor alpha(TNF-α)、matrix metalloproteinases-9(MMP-9) and vascular endothelial growth factor(VEGF) in bronchoalveolar lavage fluid(BALF) of rats with emphysema and their mutual relationship,and the effect of infliximab on them.Methods:Thirty-nine rats were randomly divided into a normal control group,an emphysema group,an infliximab-intervention group.Rat models of emphysema were established by exposure to cigarette [...]
ObjectiveTo investigate the Changed levels of peripheral blood endothelial progenitor cells (EPCs) and serum VEGF, bFGF, eNOS in rats with cerebral ischemic reperfusion injury and their correlation. We will obtain some basis for monitoring the degree of the patients with cerebral infarctionMethods50 Sprague-Dawley (SD) rats are randomly divided into the cerebral ischemic reperfusion injury group [...]
Objective:The objective is to provide the theory basis for pathological mechanism, premedicant and prevent the recurrence of Pterygium through evaluate the expression level and relationship of IGF-2, VEGF in pterygium.Methods:52 cases patients with pterygium and strabismus were selected, all the patients were surgeried in yanbian university hospital from 2009.11 to 2010.10,28. All the cases were [...]
ObjectiveDiabetic nephropathy (diabetic nephropathy,DN) is one of the serious complications of diabetes,With the aggravation of the disease could eventually lead to end-stage renal failure (ESRD),and Seriously affect the quality of life of patients,The found of that vascular endothelial growth factor(Vascular Endothelial Growth Factor , VEGF) , neutrophil gelatinase-associated lipocalin (Neutrophil gelatinase-associated lipocalin,NGAL) are both closely [...]
Objective:To explore VEGF expression between colonic adenoma of TCM syndrome types, and oberserve the correlation in different diseases and syndromes.Object and Methods:According to the criteria of inclusion, choose three syndrome types from colonic adenoma patients, every type have 20 cases,which contain Spleen wet sluggish certificate, damp and hot accumulate bowel syndrome, spleen and kidney Yang [...]
ObjectiveTo research the effects of Jinlong capsule combined with GP regimen on the expression level of vascular endothelial growth factor (VEGF) in serum, objective curative effect, chan-ges of traditional Chinese medicine symptoms and quality of life with advanced non-small cell lung cancer (NSCLC) patients.MethodsSixty cases of advanced NSCLC were divided into two groups randomly. Thirty [...]
Objective:The model of anterior segment ischemia(ASI) in rabbits after multi-rectus tenotomy in both eyes was established.To investigate the expression of VEGF in expremental anterior segment inchemia in rabbits, and inquire the contact with each other. And suramin has the inhibitory effect on VEGF. Then provide the therapeutical thinking for ASI.Materials and methods:54 purebred male Japanese [...]
Objective:To establish the method of isolation and cultivation of rat bone marrow mesenchymal stem cells(BMSCs) in vitro.To evaluate the simultaneity expression efficacy of rat bone marrow stromal cells(BMSCs) transfected with bone morphogenetic protein 2(BMP2) and vascular endothelial growth factor(VEGF) genes.Methods:BMSCs from rats were isolated and cultured in vitro by using the whole bone marrow adherence [...]
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