0bjective1 To preliminary investigate the influence on the brain derived neurotrophic factor (BDNF)expression in the brain of traumatic brain injury (TBI) rat after transplanting bone marrowmesenchymal stem cells (BMSCs) and vascular endothelial growth factor (VEGF).2 To preliminary study on combined transplantation of BMSCs and VEGF for treatment of TBIrats and its therapeutic effect.3 To establish [...]
Background:Recently some reports have confirmed single utilization of bone marrow mesenchymal stemcells in rat traumatic brain injury can enhance the recovery of the function and reduce theapoptosis in the injury area,but the effect is not obvious,it may be short of efficient vascularendorsement;vascular endothelia growth factor also can accelerate the reconstruction of thevascular in the injury [...]
ObjectiveTrough testing the serum levels of vascular endothelial growth factor and endostatin inchildren with Kawasaki disease, to explore their role in Kawasaki disease，especially Kawasakidisease with coronary artery lesion complication, to provide clinical basis for the study of Kawasakidisease pathogenesis and provide a new reference for the clinical diagnosis and prognosis of Kawasaki disease.Method35 children who [...]
Objectives EMS is a common disease during reproductive women, although it is a benign disease, it has a feature of extensive planting、high recurrence rate.OEM often has a high recurrence rates after conservative surgery, drug therapy may prevent recurrence, this study mainly focus on Nei Yi-ting formula by observing the OEM patients after conservative surgery the [...]
Purpose: To observe the Method of Activating Dieresis and replenishing Qi on TreatingDiabetic Macular Edema by the method of biochemical,pathological and RT-PCR.Method: The rats with diabetic were divided randomly into4groups:diabetes modelgroup(Ⅱ), Activating Dieresis and replenishing Qi group(Ⅲ), Calcium Dobesilate group (Ⅳ),Normal control group(Ⅰ)was also set. The Igroup and the Ⅱgroup was gastric lavage with1ml salinelavage，and [...]
Objective To explore the effects of CTGF on the expression of OPG and VEGF in fracture healing and its mechanism.Methods Forty clean male SD rats aged3to6months were enrolled.After the tibial bone fracture model was established,the SD rats were divided into experimental group and control group with20rats in each group.The experimental group was injected with CTGF [...]
Background and ObjectiveThe cornea is characterized by the absence of blood vessels under physiologicalconditions. Corneal avascularity is preserved by the balance between proangiogenic andantiangiogenic molecules and is required for optical clarity and visual acuity. Cornealneovascularization can arise from various causes, such as corneal inflammation, trauma,hypoxia and edema, which disrupt the balance between proangiogenic and antiangiogenicmolecules [...]
Background and Objective:For the purpose of increasing bone mass, autologous, allogeneic, heterogeneous andartificial bone materials are now widely used in dentistry and maxillofacial surgery.Angiogenesis in bone replacement graft is considered that play an important role insuccessful healing and bone formation. Interaction of osteogenesis and angiogenesis isregulated by a variety of factors produced by autocrine-paracrine networks, [...]
Background and aims:Diabetic foot ulcer (DFU) is one of the most severe complications of diabetics. It was reported that14%-24%patients with DFU had to eventually undergo amputation. Angiogenesis dysfunction resulting from the imbalance of microenvironment in wound surface is the main reason for protracting course of DFU. Therefore, to promote angiogenesis and to improve microenvironment will [...]
Objective:To observation the clinical effection of wan on the advanced gastric cancer patients after surgery and experimentalize to explore its Anti-transfer mechanisms.Methods:1.Clinical research:since January2011to March2012, selected hospital chemotherapy after resection of gastric cancer patients with39case, and divide them randomly into treatment group and the control group。the control group,21cases, only for chemotherapy; the treatment group,18case, treated [...]
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