Objective:To study the relationship among Insulin resistance,Isletβ-cell function and TCM blood stasis syndrome of type 2 diabetes mellitus (T2DM),and to understand the relationship between the pathogenesis of type 2 diabetes mellitus and TCM blood stasis syndrome, which provides some suggestions about the therapy of T2DM by promoting blood circulation for removing blood stasis.Methods:According to the [...]
Objective:Observe the conventional indexes and adiponectin(APN), homocysteine(HCY) levels of type 2 diabetes mellitus (T2DM) with and non-with phlegm syndromes(PS) and blood stasis syndromes (BSS), in order to reveal the objective law of T2DM with PS、BSS, to analysis the pathological role of serum APN and HCY in chronic vascular complications within patients of T2DM,to provide the [...]
ObjectiveTo study the changes of urine NGAL in patients of type 2 diabetic mellitus (T2DM) and the association of NGAL with MAU(microalbuminuria). To investigate the clinical role of NGAL in the pathogenesis of vascular endothelial dysfunction, insulin resistance.MethodsAccording to the standards of diabetic diagnosis and typing put forward by WHO in 1999, a total of [...]
Objective: To explore the effects and part mechanism of action of TFLC on experimental T2DM rat model.Method: We established type 2 diabetes mellitus rat model in an improved method. With oral glucose tolerance test (OGTT) and determination of fasting blood glucose and blood insulin levels ,the model was assessed whether established successfully. These rat models [...]
Objective 1) To detect the expression of peripheral T lymphocyte subsets and costimulators, and investigate their probalble roles in development of diabetes and diabetic kidney disease. 2) To observe the effects of Chinese medicine Shuxuetong on diabetes and diabetic kidney disease.Methods Flow cytometry was applied to detect CD3, CD4 and CD8 on T lymphocyte surface [...]
Objective:1.To study the distributive features of Traditional Chinese Medicine（TCM） syndrome of type 2 diabetes mellitus（T2DM） with dyslipidemia patients.2.To analyze the correlation between the main syndrome elements of T2DM with dyslipidemia patients and physical and biochemical indexes.Methods:In this study,the general materials and materials of the four TCM diagnosis and treat of outpatients at The No.1 Hospital [...]
Objective: To detect the plasma level of osteopontin and IL-18 as well as CD4+/CD8+ T cell ratio in type 2 diabetes mellitus (T2DM), and explore the role of OPN in the pathogenesis of T2DM .Methods: Twenty cases were selected from the patients diagnosed as T2DM for the first time from November 2008 to December 2009.The [...]
Objective: To detect the plasma level of osteopontin and IL-18 as well as CD4+/CD8+ T cell ratio in type 2 diabetes mellitus (T2DM), and explore the role of OPN in the pathogenesis of T2DM .Methods: Twenty cases were selected from the patients diagnosed as T2DM for the first time from November 2008 to December 2009.The [...]
Objective:To compare and analyze the clinical features and related factors between case group of cognitive impairment and control group of normal cognitive function among the patients with type 2 diabetes mellitus（T2DM）.To explore the risk factors of cognitive impairment and analyze the relationships between cognitive impairment and polymorphisms of ApoE gene and TNF-αgene,and provide scientific basis [...]
Part l.The epidemiological study in middle-aged and the elderly peopleIn order to study the relationship among higher fasting serurn glucose (FSG), hyperlipemia,hypertension, hyperuricemia in middle aged and elderly people, FSG, triglycerides(TG), cholesterol(TC), uric acid (UA) and insulin (INS) of serum. blood pressure (BP) and body mass index (BMI)of l477 men and women over 40 years [...]
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