OBJECTIVE: To prepare a new preparation of Chinese materia medica, Zicao spray, for allergic coryza.METHODS: The extraction conditions of lithospermi were optimized with the different concentrations of alcohol as extracting solvent and with the l-shikonin content as the index using orthogonal test. With 95% alcohol used as solvent, 1,2-propylene glycol as solvent and penetration enhancer, [...]

OBJECTIVE: To prepare a new preparation of Chinese materia medica, Zicao spray, for allergic coryza.METHODS: The extraction conditions of lithospermi were optimized with the different concentrations of alcohol as extracting solvent and with the l-shikonin content as the index using orthogonal test. With 95% alcohol used as solvent, 1,2-propylene glycol as solvent and penetration enhancer, [...]

OBJECTIVE: To preparate and evaluate Xinzhi ion-activated nasal in situ gel.METHOD : (1)The extraction conditions of volatile oil were optimized with the volatile oil content as the index .(2)The extraction conditions of medicinal materials were optimized with 95% alcohol as extracting solvent and with the Magnolin and Imperatorin content as the index using orthogonal test.(3)To [...]