Objectives:1. To investigate the effects of Ginsenoside Rgl on serum biochemical index, renal function, and renal pathology in rats with nephropathy.2.To detect the rats’ serumlevel of IL-4and TNF-α and explor the ginsenoside Rgl’s protective mechanism to kidney.3.To study the correlation relationship between ginseng tonifying primordial Qi and regulating inflammatory factors.Methods:Random samplled eight rats for normal [...]
Purpose:To observe the clinical efficacy of theray in the way of nourishing kidney and Liver with progesterone, as well as discuss the mechanism of it.Meanwhile to Investigate the TNF-α,IL-8and threatened abortion, and to provide clinical treatment.Method:Separate forty seven patients of clinic and ward into either treatment or control group randomly. Twenty-one cases among the control [...]
Due to occurrences of bleeding and reactive inflammation after limb trauma or surgery, limb swelling will appear, with the peak at3-7days induced by trauma or surgery, and pain, wound infection and deep vein thrombus are common complications. There are many restricts for conventional rehabilitation therapies to alleviate swelling in acute phase, and meanwhile conventional therapies [...]
ObjectiveBronchoalveolar lavage fluid from rats with experimentally induced allergic pulmonaryinflammation contains a novel9.4kDa cysteine-rich secreted protein, FIZZ1(found ininflammatory zone). The objective of this study was to investigate the expression of FIZZ1in thelung tissue from smoking induced COPD rats and thus explored the potential role of FIZZ1inairway remodeling in COPD.MethodsStudy population consisted in70Wistar male rats, adults,3-month-old [...]
Background:The group of Jian Li, Ph.D. Professor (Director of the Department of PharmaceuticalSciencesSchool of Pharmacy，East China University of Science&Technology) found asmall molecule compounds (HL131012) which have strong inhibition of Syk kinaseactivity in accidently, they synthesis48compounds after a series of structuralmodification in accordance with traditional medicinal chemistry for HL131012structure,then cooperating with us to verify the biological [...]
Objective:To observe the effect on mRNA expression of TNF-α and IL-1β inin ischemic penumbra of cerebral infarction model rats treated by acupuncturing DU meridian acupoints; and to explore the mechanisms of protecting ischemic brain tissue by acupuncturing DU acupoints.Methods:Using the method of plugging wire into SD rats’middle cerebral artery to make cerebral infarction model which [...]
Objectives:To detect the level of serum total protein, albumin, interleukin-6(IL-6), tumor necrosis factor-a (TNF-a) and endotoxin, to explore serum protein changes and its mechanism in acute craniocerebral trauma, in order to provide conference for clinical nutrition support and reducing secondary brain trauma.Object and method:65patients with craniocerebral trauma from January,2008to September,2011in our hospital were included in [...]
Objective To discuss the correlative change between HSP70 and TNF-a on retinal excitotoxicity injury in rats.Methods 50 Wistar rats were randomly divided into three groups, normal control group including 6 rats, the positive control group including 20 rats with intravitreal injection with NMDA and the experimental group including 25 rats with intraperitoneal injection with zinc [...]
Objective:Observe the effect of acupuncture Du meridian people, Bai Hui, the Ren Zhong, the Da Zhui of Resistance to injury and protection of the ischemic area. Observed ischemic brain tissue TNF-α and Caspase-3expression to explore acupuncture Du meridian people, Bai Hui, the Ren Zhong, the Da Zhui on the brain to produce the protective effect [...]
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