Bisphenol A(BPA) is a widespread environmental endocrine disruptor (EDC). As additives of epoxy resins, polycarbonate plastics, flame retardants and other produts, bisphenol A analogues were widely used in the production of cups, bottles, food and beverage containers, medical equipments etc, and meanwhile, new uses have been developed. In the long-term use process, or under alkaline [...]
Aflatoxins is one kind has the greatly strengthened toxic Secondary Metabolites of fungus, has created extremely serious threat to the human health. In natural pollution food by Aflatoxin B1(AFB1) most sees, its toxicity and carcinogenicity is also strongest. When the human takes in massively, has the possibility to be able to have the acute poison, [...]
After ischemic-reperfusion, the nerve cells died in form of necrosis or apoptosis. The necrosis of nerve cells in the center of ischemic area is irreversible; but the apoptosis of nerve cells in ischemic penumbra is reversible. So ischemic penumbra is a hot spot studied in ischemic cerebral vasocular diseases. Although the tissues of ischemic penumbra [...]
Objective:In our study,we analyze the workers’ chromosome aberration and micronucleus who exposed to electronic waste for a long time and with adverse pregnancy(Missed abortion,Fetal anomaly and Stillbirth fetus) combining with cytokinesis-block micronucleus and microelement test in order to estimate the degree of genome damage and explore the damaging effects of electronic pollutants on reproduction function [...]
Objective:Hydroquinone (1,4-dihydroxybenzene, HQ) is an important industrial chemical used as a developer in the photographic industry, as an anti-oxidant in the rubber industry, as an intermediate in the manufacturing of food anti-oxidants, and as a polymerization inhibitor for vinyl and acrylic monomers. It is widely used solvent in industry and daily life. Its exposure is [...]
Arsenic compound is a classical carcinogens, which has DNA damage effect on organism. Roxarsone not only has significantly effect on the DNA damage, but also has potential genetic toxicity to organism in the environment although the toxicity of roxarsone is lower than inorganic arsenic. In this paper, single-cell gel electrophoresis was used to demonstrate the [...]
Recently, the environmental endocrine disruptors’ harm to human has attracted public and academe’s attention, it has been research hot of the toxicology in the world.The growth,development,breed of aquatic organism were menaced and aquatic ecosystem were destroyed by pentachlorophenol (PCP), PCP could enter into body by food chain and produce potential danger.Hence, it is very important [...]
OBJECTIVE To establish animal model and observe the chronic effect of deltamethrin on the behavior; to study morphologic changes, DNA damage and damage repair on liver of test animals induced by deltamethrin; to evaluate DNA damage repair mechanism and significances. METHODS To use the chronic toxicity tests, and 32 female Wistar rats were randomly divided [...]
Pentachlorophenol(PCP), which is one of the phenolie compounds,can interfere with the normal incretion function of animals,and it is also an important environmental hormone.Its chemical properties are relatively stable, it can accumulate in the sediments, and it is difficult to be degraded. So the residue in the environment is relatively high.When it had been widely used [...]
Formaldehyde (HCHO) is a genotoxicant which is suspected to have the ability to induce leukemia in epidemiology field. However, little is known about the possible mechanism how this agent induces leukemia. In this study, rat marrow cells are chosen to be the exposure targets to both liquid and gaseous formaldehyde. DNA-protein crosslinks are evaluated via [...]
Hello,My name is Jack,Ph.D. Supervisor, Welcome to My WebSite