ObjectiveThrough the follow-up study of Levetiracetam(LEV) in the treatment of children with different types of epilepsies,changes of clinical symptoms, electroencephalogram (EEG) and adverse events were observed. To research the efficacy and safety of LEV therapy in children with different types of epilepsies,and to provide more reliable methods and evidences for Pediatric neural physician in the [...]
Purposes:This retrospective study was performed to evaluate the activity and toxicity of gemcitabine-based combinations as first-line treatment in patients with locally advanced and metastatic pancreatic adenocarcinoma.Methods:Previously untreated metastatic and locally advanced pancreatic adenocarcinoma patients with PS0-2, who admitted in our center between August2008to March2012, were enrolled to this retrospective study. Patients received gemcitabine-based combinations as [...]
Neopanaxadiol （NPD） was obtained from the acid hydrolysate of the total ginsenosidesof Panax ginseng C. A. Meyer （Araliaceae）. On the basis of spectroscopic data andsingle-crystal X-ray diffraction data, its chemical structure was elucidated to bedammar-（E）-20（22）-ene-3β,12β,25-triol. It can improve learning and memory ability ofdementia mice model. The satisfied pharmacological activity and safety make it to be [...]
Clinical Randomized Controlled Study of Kuikeling for the Treatment in Patients with Crohn’s Disease
Aims:The aims of this study were to observe the efficacy and safety of Traditional Chinese Medicine-Kuikeling(TCM-KKL) on the treatment in patients with Crohn’s disease(CD) and to provide the basis for guiding therapy of Crohn’s disease。Methods:In the clinical randomized controlled study,58patients with moderate-active CD were randomized into two treatment groups which were KKL and west medicine [...]
Invasive aspergillosis is a significant cause of morbidity and mortality in heavily immunocompromised patients and is associated with significant hospital costs and therapy complications in those with multiple comorbidities. Targeted pulmonary delivery by aerosolization of antifungals has recently gained attention, The use of aerosols for targeting medication to the receptor sites in the lung has [...]
Objective：1.To evaluate the efficacy and safety of endoscopic submucosal dissection(ESD)in treatment of patients with superficial digestive tract neoplastic lesions.2. Toevaluate the risk factors of complications of endoscopic submucosal dissection (ESD)intreatment of patients with superficial digestive tract neoplastic lesions. Methods BetweenJanuary2010and October2011, a total of154consecutive patients (mean age59.8±10.5years) who underwent ESD for superficial digestive tract neoplastic [...]
BackgroundRheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease, the most common manifestations of which are symmetric polyarthralgia, joint swelling and dysfunction. The pathological characteristics of RA include chronic synovial inflammation and hyperplasia, pannus formation,in the end bone erosion, cartilage loss and joint destruction. If untreated, it would lead to joint deformity and disability.Current [...]
Objective: To assess the therapeutic effect and cognitive influence ofrepetitive transcranial magnetic stimulation(rTMS) in treatment of bipolardepressive disorder．Methods: Comparative study method was adopted for four weeks.71patients of bipolar depressive disorder and30normal controls were involvedin the study.The patients were randomly assigned to lamotrigine treatment incombination with rTMS (study group) or sham procedure (control group) onleft dorsal-lateral [...]
Object iveTo observe and evaluate the safety of Jin Fu An Decoction (JFAD) in the treatment of medium or Advanced Lung Cancer.Methods60patients with medium or advanced lung cancer were randomly divided into treatment group and control one. Patients in treatment group also received the treatment of JFAD besides the best supportive care. All symptoms related [...]
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