Cryptococcus neoformans is an important fungal pathogen that causes life-threateningmeningitis which needs long time treatment and is of high rates of relapse. In the treatmentof cryptococcal meningitis and other systemic infections, an issue that perplexed theclinicians is that no accurate and efficatious judgements in regard to the vitality ofcryptococcus neoformans can be made so that [...]
A Study on the Vitality of Crypotococcus Neoformans through Detecting rRNA with the Method of RT-PCR
Objectives: Previous studies have confirmed that the application of Low dose Xirradiation (LDI) could affect the Fracture healing process, however, the mechanism ofwhich remains unclear. The aim of this study was designed to investigate the mechanismsof LDI’s promotion to fracture healing.Methods:1. BMSCs were harvested from rat fresh bone marrow and exposed to a0Gy、25mGy、50mGy、75mGy、100mGy、1000mGy X-ray irradiation. [...]
Objective: To quantify the expression of FXYD3in the human colon carcinomatissue, and to investigate the significance of relationship between the expression of FXYD3protein and clinicopathological parameters in the patients with colon carcinoma.Methods: Protein levels of FXYD3in paraffin sections of60cases of coloncarcinoma,34cases of adjacent normal mucosa and20cases of distant normal mucosawere determined by Immunohistochemical Streptavidin-perxiodase technique, [...]
Objective:To observe the expression of mutational PBRM1and mutational P53in different stages and classification of renal cell carcinoma (RCC) and normal tissue,to discuss the expression of PBRM1and P53in RCC and their correlation.Methods:Expression of PBRM1and P53was detected by immunohistochemical technique in66cases of RCC and20cases of normal renal tissues,Selected24cases fresh renal clear cell carcinoma samples and10cases of normal [...]
Objective To investigate the effections of IGF-1R and IGF1in gastrointestinal stromal tumors’ pathogenesis and their clinical significance.Method RT-PCR was used to determine the IGF-1R and IGF1mRNA expressions in40cases of gastrointestinal stromal tumors tissues and the normal tissues.By comparison,the expression of CD117in gastrointestinal stromal tumors was analyzed.Result In gastrointestinal stromal tumors, the expressions of IGF-1R and [...]
Background and PurposeAcute Leukemia (Acute Leukemia, AL), it is a serious threat to human health of cancer for it’s increased high morbidity and mortality. The characteristics of AL is the original or childish abnormal cell proliferation, differentiation and apoptosis is inhabited. The pathogenesis of AL is not clear, but research shows that it has contact [...]
Primary liver cancer (PLC) is one of the common malignant tumors. The incidence of PLC has risen in recent years. It is in fifth place, every year the new patient is about622,000and the death rate in third place. In our country, the new patients are about340,000every year, nearly110,000die from PLC, which in second place.This disease [...]
Prostate cancer is one of the malignant tumors that occur in male prostate tissue, which is resulted from prostate gland bubble abnormal cellular sprawling growth. The risk of prostate cancer has obvious geographic and racial differences. In Europe, United States and other developed countries and regions, it is the most common cancer in men with [...]
Objective To detect mRNA levels of Notch receptors in specimens organization of gastric cancer patients (cancer tissues, adjacent tissues and normal gastric mucosa) by RT-PCR technology, and to detect the expression levels of Notch receptors by immunohistochemical techniques, to analysis the relationship between of the express of these molecules and gastric cancerclinicopathological parameters, clearing the [...]
Objective To investigated the expression of TGR5and FXR in human colorectal cancer and its clinical significance.Methods thirty-six cases of cancer tissue specimens, paracancerous and normal colorectal tissues were collected from June2011to December.QRT-PCR were used to detect TGR5and FXR expression in those specimens.Result The expression of TGR5were11.97±6.39and5.61±3.62in colorectal cancer and paracancerous tissues.The difference was statistically significant. [...]
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