BackgroundRheumatoid arthritis (RA) is a common systematic autoimmune disease which characteristic is a highly disabling disease. Now, the most important treatment of RA is disease modifying anti-rheumatic drugs (DMARDs), it can reduce disability. But the efficacies of DMARDs could decrease gradually because of cell’s drug resistance. The study of drug resistance has been started in [...]
Objective:To observe the clinical effects about the granules of Xin Bi Tong Ling on treating cold-warm Bi syndrome of rheumatoid arthritis.Methods:Take30patients who were accord with cold-warm Bi syndrome of rheumatoid arthritis averagely into two groups.The control group were treated by MTX and meloxicam according to the plan.The treatment group were treated by both MTX, meloxicam [...]
Objective:”Stasis hot pathogenesis syndrome factor” is relying on two new academic ideas which ZhouZhongYing professor put forward the pathogenesis and heat and blood stasis syndrome factor in the process of rheumatoid arthritis,”stasis hot pathogenesis syndrome factor” as the breakthrough point is changed。Through the grasp of “heat and blood stasis syndrome factor pathogenesis ” dynamic development, [...]
ObjectiveTo investigate the correlation of anto-immune antibodies and the kidney-deficiency type rheumatoid arthritis (RA). It would provide clinical evidence for the further research of molecular biology mechanism in RA patients with kidney-deficiency.MethodsThere were451patients with RA totally in this research,218cases with kidney-deficiency,233cases without kidney-deficiency. Statistical analysis was employed in general condition (gender, age, duration and age [...]
Objectives:By analyzing、summarizing the high frequency of drugs, according to nearly10years the literature of Traditional Chinese Medicine treatment of rheumatoid arthritis,to study the rheumatoid arthritis TCM syndrome and drug law, finish the TCM therapeutic mechanism and Chinese materia medica Pharmacology.Methods:According to TCM clinical research literatures about rheumatoid arthritis, which published in biomedical journals CKMD, CQVIP, wanfangdata [...]
Objective: To analyze the serum levels of Toll-like receptor7(TLR7) in Collagen-Induced Arthritis(CIA), and to investigate the role of serum TLR7in pathogenesis ofrheumatoid arthritis (RA).Methods: Thirty DBA/1mice were randomly divided into three groups: normalcontrol group, model group and treatment group. CIA were established by immunizingmice with cow TypeⅡCollgen and complete Freunds adjuvant. Arthritis Index(AI) wererecorded after [...]
Objective：The present study was designed to investigate the interactionbetween disease activity score and inflammatory markers in rheumatoidarthritis (RA) subjects；explore sensitive indicator of early assessment ofdisease activity; investigate influence of biological agents on inflammatorymarkers in rheumatoid arthritis (RA) subjects.Methods: Retrospective analysis of the DAS28score and inflammatorymarkers in134patients with RA; Before and after comparison of theapplication of [...]
Rheumatoid arthritis (RA), which main pathological changes are chronic,progressive arthromeningitis and vasculitis, is a chronic, systematic andinflammatory autoimmune disease mainly involving around joints. Theprevalence rate of RA which has high morbidity and mortality is nearly0.36%in our country. With the increasing levels of the treatment, survival time ofpatients is extending gradually. However, Cardiovascular events is the [...]
Objective: Our research is mainly to inquire the differences about clinical features,health checkups and laboratory examinations between the HLA-B27positive and negativepatients with rheumatoid arthritis. And attempt to discover the dependency of the diseaseactivity index and disease activity score between HLA-B27and RA, which can provide theclues and evidences for early diagnosis, disease progression and prognosis judgment [...]
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