Background And Objective:NS5ATP9is a trans-activator gene of HCV NS5A protein, screened by suppression subtractive hybridization (SSH). The present study shows that NS5ATP9gene is associated with a variety of tumor tissue. It involved in DNA repair, cell signaling pathways and the regulation of cell proliferation. But the reports about NS5ATP9expression in human tissues and cell lines [...]
Introduction:Cortex Ailanthi Ailanthus altissima (Mill.)Swingle is a herb that has been found to have a wide range of functions, such as clearing away heat and eliminating dampness, astringent for spermatorrhea and excessive vaginal discharge, relieving diarrhea, arresting bleeding and insecticide. It can be used in the treatment of anti-inflammatory, leukorrhea with reddish discharge, hot and [...]
The Preliminiary Study of TLR4and Costimulatory Molecular B7-H3Expression in Colon Cancer SW480Cells
Objective: To illustrate the expression of TLR4and costimulatory molecular B7-H3in human colon cancer cell line.To investigate the interfering efficiency of TLR4siRNAand the effect of the silence on TLR4and B7-H3expression.Methods:1. To establish quantitative real-time PCR methods for detecting TLR4andB7-H3expression.Take the SW480cells of logarithm growth period to experiment. Thetotal RNA was isolated using the Centrifugal column way,then [...]
Objective GOS is a prebiotic, it has many research about the impact of prebiotics on the intestinal mucosal barrier and the gut microflora mechanism. It has achieved good results in animal experiments. First, it can promote gut microflora balance and the growth of beneficial bacteria; second, it does not absorb, digest features, thus avoiding the [...]
Objective To explore the expression and clinical significance of RACK1in the peripheral blood of coronary atherosclerosis, and to study the relationship between the RACK1and the extent of coronary lesions in patients who were examined by CAG.Methods A total of83coronary atherosclerosis patients were enrolled. According to the results of angiography, the coronary stenosis score was used [...]
Objective: To investigate the expression level and clinical significance of microRNA-21(miRNA-21) and microRNA-205(miRNA-205) in non-small cell lung cancer (NSCLC)patients’ bronchoscopy tissue and plasma．Methods：To quantified the expression level of miRNA-21and miRNA-205in thirty oneNSCLC cases and ten controls with Real-time PCR，then compared the expression level ofeach microRNA between the two groups and analyzed correlation between the expressionlevel [...]
ObjectivesColorectal carcinoma (CRC) is a common gastrointestinal malignance all over the world. Recently, the incidence of CRC is in increasing in China. There is a close relationship between the immunologic dysfunction and the development of CRC. CRC expresses many tumor associated antigens (TAAs) that can be recognized by human immune system, and host immunity tries [...]
Part OneMigration consistent with a benign treatment of hilar bile duct strictureObjectiveTreatment of hilar bile duct benign stricture of a new technique to explore transitional anastomosis. Obtained hilar bile duct benign stricture transitional anastomosis theoretical basis and practical application feasibility, indications and contraindications, looking for more in line with the anatomy and physiology surgical approach [...]
BackgroundWorld health organization reported that, ischemia heart disease will be the second threat ofcivil health in 2030.Among all the causes of ischemia heart disease, ischemia myocardiuminduced by coronary artery infarction must be the most important one. The increasing prevalenceof coronary artery disease (CAD) with high mortality and morbidity in our nation has been oneof the [...]
As a most frequent malignant tumor, thyroid cancer has a variant growth behavior. 98% of the cancer can be classified as Differentiated Thyroid Cancer (DTC). Although with low malignancy, it is reported that from 20% to 40% of the DTC patients still suffer from the recurrence. So the early diagnosis and follow-up to patients after [...]
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