Epinephrine is the most widely used vasoactive drug in clinic. Usual doses of epinephrine intravenous injection can increase blood pressure and enhance myocardial contractility which is used in some life-threatening circumstances, including the treatment of cardiac arrest, circulatory collapse, and anaphylaxis. Recently, there were many reports indicated that epinephrine nasal or scalp infiltration or endotracheal [...]
The animal experiments show that lipid emulsion infusion can lessen and reverse heart toxicity of local anesthetic, which is also demonstrated by clinical studies. In the early stage, lipid emulsion therapy not only can prevent cardiovascular toxicity but also relieve nervous system toxicity. However, the mechanism that lipid emulsion remedies general toxicity of local anesthetic [...]
ObjectiveTo observe the efficacy and safety of sulodexide on patients of type2diabeticnephropathy who have received ACEI and/or ARB therapy.MethodsA total of92cases of type2diabetic nephropathy patients, who had received at leastone kind of ACEI and/or ARB drug therapy for at least6months, were devided into twogroups: the microalbuminuria group and the macroalbuminuria group. All the patients weregiven [...]
Background and ObjectivesGDM is seriously endangering the health of mothers and babies and is closely related to a variety of adverse pregnancy outcomes. Currently, most people believe that insulin resistance is one of the common pathogenesis of GDM and type2diabetes. The impact of environmental factors on insulin resistance has aroused widespread concern. Studies have shown [...]
Objective To investigate the expression and distribution of adiponectin(APN) in periodontium during orthodontic tooth movement in rats.Methods Thirty-five male SD rats (200-250g,9-week-old) were randomly divided into seven groups, containing one control group(without orthodontic appliance) and six experimental groups(orthodontic appliances were used for1,3,5,7,10,14days, respectively). Each group contained five rats. Tooth movement was induced by a nickel-titanium(Ni-Ti) [...]
ObjectivesThe aim of this study was to compare the pharmacokinetics differences of glibenclamide by intragastrical/intravenous administration between normal rats and two models of diabetic rats, and the mechanism of difference was preliminarily clarified.Methods1. Wistar rats were divided into3groups, A:normal rats （normal group）; B:streptozotocin （STZ） induced diabetic rats （STZ group）; C:high-energy diet plus STZ induced diabetic [...]
Background and Objective: Spermatic cord torsion is a commonurologic emergency. Each year, spermatic cord torsion affects one in 4,000males younger than 25 years. Orchiectomy rates ranged from 39% to 71% asshown in most studies. It is controversial whether we should carry outdetorsion to preserve the ipsilateral testis, or perform an orchiectomy topreserve the function of [...]
Background and Purpose:Susceptibility Weighted Imaging (SWI), which employs phase information induced by tissues with various susceptibilities to improve the image contrast, is well known for its superior ability in detection of hemorrhage, microbleeds and even iron deposition in human brain diseases. In this study we use SWI (1) to detect the distribution and prevalence of [...]
Objective(1) To research the effects of neural stem cell transplantation in the treatment of Parkinson’s disease.(2) To explore the molecular mechanisms of neural stem cell transplantation in the treatment of Parkinson’s disease by SDF-1/CXCR4signal transduction pathway.Methods(1) To dissect the neural stem cells in the ventri-mesencephalon of E14d rats embryo and to culture those cells in [...]
Objective:This study through the pregnancy low protein diet method to set up the animal models of intrauterine growth retardation(IUGR),to observe the change of expression to growth associated protein43(GAP-43)in the brains of IUGR neonatal rats at different parts of the organization and different development stages,and analyze the role of GAP-43in the brain development and function abnormality [...]
Hello,My name is Jack,Ph.D. Supervisor, Welcome to My WebSite