Objective:To observe2diabetic (DM) rat, that after inject with insulin, the expression of bone morphogenetic protein2(BMP-2). To investigate the expression and meaning of the morphogenetic protein-2that influenced of insulin in type2diabetic rat peri-implant bone.Methods:1.30type2diabetic rats(weight200-220g) were divided into3groups:normal group, diabetic group and diabetic+insulin group.2.Type2diabetic model rats were fed on high-glucose-high-fat diet and injected by low dose [...]
Learning and memory function is an important function of human knowing andadapting objective world，to explore drug of enhanceing Learning and memory function is animportant task of pharmaceutical and medical science field.Anti-dementiaⅠ i mprovedLearning and memory function of VD and AD rats inearlier study. Anti-dementia Ⅰimproved Learning and memory function andalleviated pathological change of VD rats [...]
Objective Learn by observing the pain behavior changes of the chronic CIPN rat model,observing the expression changes of NR2B in spinal cotd dorsal horn and pNF-H in dorsal root ganglion neurons,to explore Dangguisini soup on the preventive efiect of oxaliplatin induced chronic CIPN.Methods52adult Wistar female rats were randomly divided into five groups: blank group,model group,control [...]
ObjectiveAtherosclerosis(AS)is a major cardiovascular disease pathology. ASis mediated by a variety of inflammatory mediators, which is the injuryperiod of a variety of chronic inflammatory response on arterial wall.This suggests that inhibition of AS is the useful strategy which canprevent the inflammation reaction of cardiovascular disease. Diabetes andAS are closely related, AS of diabetic patients occur [...]
ObjectiveBy using a long-term intervention with low protein diet (LPD), the study is designed toexplore alterations of uric acid, renal function and morphology, urine albumin excretion, hepaticgene expression of key enzymes involving in uric acid synthesis, as well as renal inflammatoryfactors expression in streptozotocin(STZ)-induced diabetic rats.MethodsThirty STZ-induced rats were fed with LPD and normal protein [...]
Objective Although,many studies have found that exercise training can promote the restoration of functions of patients with cerebral infarction,the study of training intensity has become more and more important.How long the rehabilitation therapy period should be to gain the best results for functional restoration and whether the intensive training(increase recovery time)can improve clinical outcomes haven’t [...]
Objective To investigate the effects of Chaihushengshitang on IL-10and VEGF in Serum and BALF of Asthmatic Rats and explore the mechanism of treating asthma with Chaihushengshitang.Methods Eighty-four male Wistar rats were divided randomly into seven groups: normal control group,model control group,dexamethasone group,dingchuantang group, chaihushengshitang low dose group,chaihushengshitang middle dose group chaihushengshitang high dose group,each group [...]
Objective:To investigate the promoting mechanism of Flavored Astragalus and Cinnamou twig five ingredients decoction n regeneration and repairation of the injured peripheral Nerve.Methods:Peripheral nerve injury model was set up by cuting the left sciatic nerve of rats.54model SD rats were randomly divided into A group、B group and C group and administered respectively with Flavored Astragalus [...]
Objective:To investigate the effect of purified liqiud in scorpion (PLIS) on arterial venous thrombus, in order to afford a new approach for seeking an effective antithrombosis medicine from chinese medicine.Methods:The rats were randomized into five groups:blank group,control group and3doses PLIS group, The effects of PLIS in different doses were investigated in the venous thrombus models [...]
Objective：To investigate the effects of clopidogrel on MSCs ttreatment to myocardialinfarction in rat.Methods：According to the different adherent characteristic of cells, isolate andculture MSCs from the tibia and femur of aged6weeks SD rats. And the passage3th cellswere used to the experiment. In vitro: use flow ctometry to detect the effect of3mg/Lconcentration of clopidogrel on MSCs’ apoptosis, [...]
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