Objective:This study was using genetransfer way that treated some disease which had noneffective form routine drugs or traditional therapeutics. And then understand how the effective of VEGF165 plasmid gene expression in tissue at after genetransfer. At the same time we observed pathological change of masseter injury of radiated rats and the level of TGF-β1 gene [...]
BACKGROUND Patients with congenital heart disease are usually associated with a lot of neopathy,and pulmonary arterial hypertension is the most common complication which affacts the prognosis of patients. The current treatments mainly includes pharmacotherapy、Surgery. The patients that are not suitable for surgery or their postoperative function are not improved can use drug therapies.The drugs,such as [...]
Objectives:This study was designed to observe the influence of rat liver after drinking several edible liquor, and analyze amino acids and aroma compositions of the several edible liquor.Methods:Eight weeks age male Sprague-Dawley rats were randomly divided into nine groups:control group, maotai(The following called NO.1 liquor) high and low dose group, xijiu(The following called NO.2 liquor) [...]
With the improvement of living standards, oral health literacy and pursuit of beauty, people have a more understanding of the malocclusion. The number of patients who turn to orthodontics for better aesthetics and function increase. However, Patients’pronunciation, chewing and appearance are affected by different degrees during orthodontic treatment. Orthodontic treatment is the process that alveolar [...]
Objective:To investigate the influences of temperature on SCF/c-kit proliferation pathway and cell cycle of spermatogonia through rat spermatogenic cells cultured in vitro at different temperatures, to provide basic research data for the mechanism of spermatogenic impairment due to body cavity temperature (37℃).Methods:The isolated spermatogenic cells from adult male SD rat using mechanical methods and enzymatic [...]
ObjectiveTo investigate sustained hyperuricemia effect of the function of endothelial cells, and further research on mechanism of the dysfunction of endothelial cells.MethodsHyperuricemia models were induced in 20 male Sprague Dawley rats for 12 days with uricase inhibitor, Oxonic acid (750 mg/kg/day), by gavage. Blood was collected by puncturing of the retrobulbar venous plexus at 0,4th,8th [...]
This thesis centers on the role of p38 Mitogen-activated protein kinase signaling pathways in inhibiting insulin resistance in myogenic IL-6. It investigates the changes of p38MAPK and the expression of IL-6 organizations and their function in improving or inhibiting the insulin resistance on rats with the intervention of sports and high-fat diet and the injection [...]
The key points of atherosclerosis formation are lipoprotein dysfunction, endothelial damage and inflammation. TFA contributing to atherosclerosis is also intrigued by these factors. Epidemiologic studies have demonstrated that TFA has the negative impacts on blood lipid (raising LDL-C and TG as well as lowering HDL-C) and increases inflammation and endothelial damage.The content, category and distribution [...]
Objectives:To study the effects of fear stress on experimental rats asthma so as to guide the clinical practice.Methods:1. Grouping and Model building:Thirty-two healthy male grown-up SD rats were divided into four groups by means of random number table:the control group (group A), the asthma group (group B), the fear stressed group (group C) and the [...]
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