BackgroundLeukemia is the most common hematological malignancy with rapid progression and poor prognosis. The incidence rate of leukemia in China is 4-7/10 millions. MicroRNAs (miRNAs) are an abundant class of 19-25 nt nucleotide small noncoding RNA molecules, which are widely found in eukaryotes. They can regulate gene expression through either inhibiting the translation or promoting [...]
Objective: c-myb gene is the cell prototype of v-myb carried by AMV and E26, located in 6q24, belongs to the nuclear proto-oncogene proteins, c-myb gene encodes a product of the c-myb protein, which is a nuclear transcription factor. The function of c-myb in the proliferation and differentiation of immature hematopoietic cell is clear and its [...]
Objective:We study the clinical and pathological data of endometrial carcinoma to investigate the prognostic factors of endometrial carcinoma and the correlationship.Methods:The clinicopathologic and surgical records of 298 patients who were diagnosed with endometrial carcinoma from January 2003 to December 2007 in Qilu Hospital of Shandong University were retrospectively reviewed. The inclusion criteria were as follows:(1) [...]
Objective:To probe into the clinical features and treatment of the patients with calcified meningiomas (CMs).Methods:We analyzed retrospectively the clinical data of 58 patients with CMs confirmed by CT, operation and pathology from January 1999 to June 2009 in QiLu hospital of Shandong University. The characteristics of epidemiology, clinical manifestations, radiological features, microsurgery, pathological subtypes, prognosis [...]
ObjectiveTo probe into expressions of p53 protein, p16 protein as well as nm23 protein, and the correlation between expression of p53 protein, p16 protein as well as nm23 protein and clinical pathological factors of lung cancer as well as prognosis, rendering an impersonalevidence for the early diagnosis, early therapy, and prognosis estimation.MethodsThe expressions of p53 [...]
Objective:To study the effect of mild hypothermia combined with TP-5 to T lymphocyte subsets and prognosis of patients with severe traumatic brain injury. Metheds:All 42 patients with severe traumatic brain injury (Glasgow coma scale score of 8 or less on admission) were randomly divided into the mild hypothermia combined with TP-5 group [experimental group,22 case] [...]
Objective:To study the clinicopathologic parameters of pancreatic endocrine tumors (PETs), examined the expression of CD99 in PETs and analysed the correlation with clinicopathologic parameters, investigated the value of CD99 in predicting biological behavior and clinical prognosis of PETs.Methods:To analyze the clinicopathologic parameters of 34 PETs, including tumor size, functional status, histological classification, local invasion or [...]
Object: To evaluate the longterm efficacy and the impact factors of prognostic of PHC with TACE.Methods:143 patients with PHC underwent TACE from January 2003 to August 2009 were retrospectively studied. The survival rates were calculated by the Kaplan-Meier method, the univariate analyses for the factors affecting survival: age, sex, HBsAg, Child-Pugh score, serum alpha-fetoprotein level, [...]
Objective:To investigate the four pathology variables recommended by IgA nephropathy Oxford classification and its relationship with prognosis of IgAN.Methods:Clinical and pathological data of 157 patients(80 males and 77females)with primary IgA nephropathy confirmed by renal biopsy in Gui Zhou Provincial People’s Hospital from June 2005 to June 2010 were reviewed retrospectively and were correlated with outcomes. [...]
Objective:To explore the risk factors influencing the survival time of the patients with multiple myeloma(MM) by analysing the presenting features and the prognostic factors. And to compare and analyse the Durie Salmon(DS) and International Staging System(ISS) staging systems of the patients with MM.Methods:Retrospective study was applied to analyze the clinical data of 81 MM cases [...]
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