Objective To explore the effects of CTGF on the expression of OPG and VEGF in fracture healing and its mechanism.Methods Forty clean male SD rats aged3to6months were enrolled.After the tibial bone fracture model was established,the SD rats were divided into experimental group and control group with20rats in each group.The experimental group was injected with CTGF [...]
Background and ObjectiveCerebrovascular disease incidence present to be increasing year by year, carotid atherosclerotic plaques is the main risk factor of cerebrovascular disease, and relates cerebrovascular disease occurrence and development closely, it is of great significance for cerebrovascular disease prevention and control to study the carotid atherosclerotic plaque risk factors. High blood pressure, diabetes, hyperlipidemia, [...]
Objective To investigate the relationships between serum osteoprotegerin(OPG)/receptor activator of nuclear factor kappaB ligand (RANKL),25-(OH)VitD3levels and osteoporosis with type2diabetes mellitus. Correlations between serum OPG/RANKL,25-(OH)VitD3levels and age, sex, duration of diabetes, plasma glucose levels, sex hormone levels and bone mineral density will be analyzed.Methods According to their bone mineral density (BMD)level,250patients with type2diabetes were divided into [...]
Objective To investigate the effect of extracorporeal shock wave on the change ofosteoprotegerin in blood plasma and osteoprotegerin expression in glucocorticoid-inducedfemoral head necrosis rabbits.Methods Fifty-four healthy adult male Japanese rabbits, random selection18as controlgroup (group A),other36rabbits were given Methylprednisolone Sodium Succinate andlipopolysaccharide for establishing glucocorticoid-induced necrosis models of femoral head,after medicined then randomly divided into model [...]
Objective: To investigate the relationships between the osteoprotegerin gene T950C and G1181C polymorphisms, blood lipids, bone mineral density and carotid artery plaque formation in postmenopausal women, so that to explore the relationship of osteoporosis and carotid artery plaque formation.Methods: (1) Selecting 236 unrelated postmenopausal women, and dividing the subjects into the following groups according to [...]
Objective: To investigate the relationships between the osteoprotegerin gene T950C and G1181C polymorphisms, blood lipids, bone mineral density and carotid artery plaque formation in postmenopausal women, so that to explore the relationship of osteoporosis and carotid artery plaque formation.Methods: (1) Selecting 236 unrelated postmenopausal women, and dividing the subjects into the following groups according to [...]
Objective: To investigate the relationships between the osteoprotegerin gene T950C and G1181C polymorphisms, blood lipids, bone mineral density and carotid artery plaque formation in postmenopausal women, so that to explore the relationship of osteoporosis and carotid artery plaque formation.Methods: (1) Selecting 236 unrelated postmenopausal women, and dividing the subjects into the following groups according to [...]
Objective: To investigate the relationships between the osteoprotegerin gene T950C and G1181C polymorphisms, blood lipids, bone mineral density and carotid artery plaque formation in postmenopausal women, so that to explore the relationship of osteoporosis and carotid artery plaque formation.Methods: (1) Selecting 236 unrelated postmenopausal women, and dividing the subjects into the following groups according to [...]
Objective: To investigate the relationships between the osteoprotegerin gene T950C and G1181C polymorphisms, blood lipids, bone mineral density and carotid artery plaque formation in postmenopausal women, so that to explore the relationship of osteoporosis and carotid artery plaque formation.Methods: (1) Selecting 236 unrelated postmenopausal women, and dividing the subjects into the following groups according to [...]
Objective: Rheumatoid arthritis (RA) is a kind of disease characterized by synovial hyperplasia and destruction of cartilage and bone. At present, it is confirmed that disease modifying antirheumatic drugs (DMARDs) have the control action for bone destruction, but have finite efficacy, obvious side effect and expensive cost. Fibroblast-like synoviocytes (FLS) are direct effectors of tissue [...]
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