Objective:To summarize the clinical and pathological characteristics of gastrointestinal stromal tumor with liver metastases and to explore its principles of diagnosis and treatment.Methods:We retrospectively analyzed the clinical data of20patients with liver metastases who had a completely case history in our hospital from October2009to October2010.Results:Among20patients, the median age was55.5(17-80).13cases were confirmed by pathological examination and7patients were [...]
07. January 2013 · Comments Off · Categories: Oncology · Tags: diagnosis, gastrointestinal stromal tumor, Imatinib, Neoplasm metastasis, treatment
21. December 2012 · Comments Off · Categories: Oncology · Tags: Neoplasm metastasis, Spine, surgicaltreatment, Thoracic and Lumbar Vertebrae, treatment outcome
Objective：To investigate the effect of resection for thoracic and lumbar metastatictumors and the relationship between the treatment result and influential factors.Methods: From September2003to August2010,there were40cases who underwentsurgical treatment because of thoracic and lumbar metastatic tumors in the department oforthopedics of the Fourth Affiliated Hospital of SuZhou University. We adoptedquestionnaire investigating way, telephone and out-patient callback [...]
29. November 2012 · Comments Off · Categories: Oncology · Tags: Colorectal Carcinoma, Neoplasm metastasis, osteopontin, VEGFlmmunohistochemistry
Objective Research the expressions of OPN and VEGF in colorectal carcinoma, adenoma and normal mucosal tissues and their relationship with clinicopathological factor.Methods In this experiment,40samples of colorectal cancer,20samples of colorectal adenoma and40samples of normal mucosa specimens were studied. To detect the expression of OPN and VEGF in specimens by S–P immunohistochemical method.Results①ne positive expression rates [...]
12. June 2012 · Comments Off · Categories: Oncology · Tags: Gastrointestinal stromal tumors, Neoplasm metastasis, Prognosis, recurrence
Objective:To investigate the clinical characteristics,treatment and prognostic factors of postoperative recurrent-metastatic gastrointestinal stromal tumor (GIST). Methods:Retrospective analysis of Dalian Medical University from March 1999 to March 2008 for the first time 123 cases of surgical treatment of recurrent and metastatic GIST patients the clinical features of 85 patients, treatment and assessment of prognosis.Results: 85 cases [...]
03. June 2012 · Comments Off · Categories: Oncology · Tags: Cell differentiation, Extracellular matrix metalloprotease inducer (EMMPRIN/CD147), Neoplasm metastasis, osteoclasts, Osteolysis
BACKGROUND AND PURPOSES:Bone, as well as liver and lung, is one of the most preferential metastatic target sites for cancer including prostate, breast, and lung cancers. Up to 70% of prostate or breast and approximately 15-30% carcinoma of lung and other solid tumor will develop bone metastasis. Once the cancer occur bone metastasis, the cancers [...]
03. June 2012 · Comments Off · Categories: Oncology · Tags: 95-D, bone metastasis, bone tumor, hFOB1.19, Lung cancer, MCP-1, Neoplasm metastasis, osteoblast, osteoclast
Background:Bone is one of the most common sites of metastatic tumor. The Incidence of bone metastatic tumors in the body was No.3, only after lung metastases and liver metastases. Prostate cancer, breast cancer, lung cancer, kidney cancer and thyroid cancer are common tumors which prone to metastasis to bone. Bone metastases means lower survival rate, [...]
19. April 2012 · Comments Off · Categories: Oncology · Tags: Breast neoplasms, Circulating tumor cells, hMAM mRNA, Neoplasm metastasis, Reverse transcription polymerase chain reaction
ObjectiveTo establish SYBR Green I Q-RT-PCR method for detection of the quantification of hMAM mRNA in peripheral blood and breast cancer tissues and corresponding adjacent breast tissues of breast cancer patients;To investigate the feasibility of hMAM mRNA as a marker of CTCs and to analyze the correlations bettween CTCs in the peripheral blood of breast [...]
14. April 2012 · Comments Off · Categories: Oncology · Tags: E-cadherin, hypoxia inducible factor 1α, Neoplasm metastasis, rectal cancer, Snail
Objective To investigate the expression of hypoxia-inducible factor-1α(HIF-1α) and E-cadherin and Snail proteins in rectal carcinoma and their significance.Methods: We retrospective analysis the 101 rectal cancer patients’clinicopathologic data from Jan 2001 to Dec 2002 of our hospital who had undergone radical surgery, and detect the expression of HIF-1αand Snail and E-cadherin proteins by using immunohistochemical [...]
12. April 2012 · Comments Off · Categories: Oncology · Tags: Endocan, endocan (human endocellular-specific molecule-1, ESM-1, immunohistochemistry, In situ hybridization (ISH), Lung neoplasms, Neoplasm metastasis
Purpose We evaluated the expression of endocan in lung cancer tissues and studied the clinicopathological characteristics and its clinical significance in lung cancer tissues.Methods The 82 cases,including 62 cases of lung cancer tissues and 20 cases of nontumoral lung tissues,were evaluated by S-P immunohistochemistry / in situ hybridization(ISH).Results The high expression rate of endocan protein [...]
12. April 2012 · Comments Off · Categories: Oncology · Tags: CD24, cell adhesion molecules(CAMs), laryngeal squamous cell carcinoma, Neoplasm metastasis, sLe~x
Laryngeal carcinoma (LC) is one of the common malignant tumors in head and neck,the incidence of LC shows an upward tendency.The highest incidence of LC is in the northeastern region,and accounting for 5.7%～7.6% of the total malignancies.The invasion and metastasis of Laryngeal cancer ,which is a multi-step, multi-stage complex process.In this process,the malignant growth of [...]
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