OBJECTTo observe the safety of HA nanoparticles as the vector of hGM-CSF gene transfection, and its impact on the growth of hepatoma carcinoma cells; hepatoma carcinoma cell vaccine was produced by hGM-CSF gene transfected cells to lay the foundation for further studying of gene-modified tumor vaccines of hepatoma in clinic.METHODSFresh hepatoma carcinoma tissues were collected, [...]