Objective:To observe the effect of salvianolic acid B postconditioning on morphology and biomechanics of decellularized porcine aortic valve, providing theoretical support for tissue engineering.Methods:Fresh aortic valves from porcine of6to7month were divided randomly into three groups(40valve leaflets in each group).Porcine aortic valve leaflets were treated by two different methods. Control group1involved treatment with Triton-x100、sodium deoxycholate、DNase and [...]
Hypertension is chronic diseases with arteriolosclerosis, the main manifestation isarterial blood pressure continues to rise. It often cause lesions of heart, brain, kidneysand other organs. Hyperlipidemia is a systemic disease, which refers to the fat runningmetabolic abnormalities makes one or a variety of lipid of plasma increase beyond thenormal range, which can directly accelerate systemic [...]
Objective: To investigate the effects of nicotine on surface morphology, proliferation andapoptosis in human umbilical cord mesenchymal stem cells (hMSCs),and to analyze the signalpathway and the changes of differential protrin expression profile,find out the target of nicotineon hMSCs. In order to provide experimental basis for hMSCs in treatmenting thesmoking-related disease.Methods:(1)The surface morphology of hMSCs before [...]
BackgroundTrichosporon is a genus of adelomycete，a class of blastomyces，Cryptococcales，Saccharomycetaceae that is common in nature and a member of the normal flora of the mouth,skin, and nails. It causes superficial infections and systematic or disseminated trichosporonosis，It can found mainly in immunocompromised patients or patients with cancer, respiratoryinsufficiency, chronic renal insufficiency, underlying hematologicmalignancies,diabetes,cirrhosis and AIDS. The main [...]
For cancer therapy, optimization of carrier features is necessary to effectively deliver the targeting agents to tumor sites. Biodegradable poly(ether-anhydrides) micelles with spherical (S), rod-like (R) and filamentous (F) shapes are fabricated.Their size and morphology are characterized by Zetasizer, Atomic force microscope (AFM) and Transmission electron microscope (TEM).The doxorubicin hydrochloride (DOX) was used as the [...]
Background and purpose:Ethanol is an ester dissolving solvent, and it can enter the brain through the blood. And it produced the toxic function directly in brain nerve cell. Ethanol can cause the damages of nerve system. With the rising of ethanol density in the blood, people’s attention, judgement and discrimination will be decreased in various [...]
Objective:To compare the effect of direct cover vitrification with hemi straw vitrification on the morphology and ultra microstructure of different stages of follicles of rabbit ovarian tissue.Methods:10healthy female rabbits were bilateral ovariectomized and each ovary were randomly divided into three groups which were the fresh group,the direct cover vitrification group and the hemi straw vitrification [...]
Hydroxyapatite (HAP) is highly similar to natural bone and tooth in the chemicalcomposition and microstructure, so it has been widely used as hard tissue restorative materials.Origniating from biomineralization, HAP crystals in natural bone and tooth were nano-flakesand hexagonal rods repectively, which are different from those of conventional synthetic HAP.In this study, on the basis of [...]
Part I Preliminary research on isolation, culture and morphology of olfactory ensheathing cells from miceObjective:To investigate different approaches to in vitro culturing olfactory ensheathing cells (OECs) from mice to obtain highly enriched population, better activity and appearance of OECs for certain experiments. Methods:Olfactory bulbs were obtained from4BALB/C mice aged2to3months, through foramen magnum for preparing cell [...]
[Background]Colorectal cancer (CRC) is one of the higher incidence of gastrointestinal cancer, the world’smost common malignancies in fourth place, the mortality rate has leapt to second place in themalignant tumors in our malignant third. Relatively low due to the rate of early diagnosis ofcolorectal cancer and found that more than in the middle and late [...]
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