Iron accumulation can cause or worsen liver damage, meanwhile liver damage often accompanies with the existence of iron accumulation phenomenon. Some researches showed that liver Kupffer cell is a key factor between iron accumulation and liver damage. However, the mechanisms are still unknown and need to be further studied.ObjectivesThe chronic model of carbon tetrachloride-induced hepatotoxicity [...]
Objective: The purpose of this experiment is to copy a progressive intracranialpressure with brain death model, observe the vital signs in the process of induction ofbrain death and brain death to cardiac death. Investigate the damage of the liver in thestate of brain death and its mechanism. Explore the Astragalus polysaccharide (APS)on the liver in [...]
Objective: The purpose of this experiment is to copy a progressive intracranialpressure with brain death model, observe the vital signs in the process of induction ofbrain death and brain death to cardiac death. Investigate the damage of the liver in thestate of brain death and its mechanism. Explore the Astragalus polysaccharide (APS)on the liver in [...]
Objective: To investigate the correlation between the severity of acute pancreatitis (AP) in MSCT images and liver function,to learn the relationship between the Acute Pancreatitis severity and liver damage probability. According to their correlation to evaluate and predict the probability of liver damage.Methods: Retrospective analysis 60 cases of acute pancreatitis with MSCT images and clinical [...]
Objective: To investigate the correlation between the severity of acute pancreatitis (AP) in MSCT images and liver function,to learn the relationship between the Acute Pancreatitis severity and liver damage probability. According to their correlation to evaluate and predict the probability of liver damage.Methods: Retrospective analysis 60 cases of acute pancreatitis with MSCT images and clinical [...]
Objective: To investigate the correlation between the severity of acute pancreatitis (AP) in MSCT images and liver function,to learn the relationship between the Acute Pancreatitis severity and liver damage probability. According to their correlation to evaluate and predict the probability of liver damage.Methods: Retrospective analysis 60 cases of acute pancreatitis with MSCT images and clinical [...]
Background and ObjectiveEnd-stage liver disease is the end stage of acute and chronic liver disease, often accompanied liver failure. The traditional treatment of end-stage liver disease is limited and leads to high mortality. Liver transplantation is the most effective treatment to date. However, this treatment can not be generally carried out because of lacking donor [...]
Background Trichloroethylene (TCE) is an organic solvent mainly used as degreaser in industry. Occupational exposing to TCE, workers appear dermatitis (DMLT) with liver injury, and it has become a major occupational health issue now. In recent years, there are many studies on the mechanism of skin injury, which considered it as delayed-type hypersensitivity. DMLT patients [...]
In recent years, cyanobacteria blooms become more frequent, resulting in a great harm to human health by its products microcystin (Microcystin, MCs). The results show that liver is the principal target organ of microcystin toxicity. Long-term and chronic exposure can even lead to liver cancer. Early studies mainly focused on the toxic effects of MCs [...]
Biological transformation of chemical substances normally undergoes two metabolizing phases called phase 1 and phase 2 metabolism in the liver.During the phase 1 metabolism, oxides and toxins are inactivated through direct reaction with small molecules such as GSH, glucuronic acid, vitamin E,etc. to reduce the harm to the body. This reaction generally is fast. During [...]
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