Objectives:To observe and analyze the effect of antitumor and anti-angiogenesis of rh-endostatin. To compare effect of rh-endostatin on microvasculature in tumor, myocardium and renal tissue. To investigate the mechanism of cardiovascular system’s adverse effect of endostar in order to direct it’s clinical application.Method:Nude mice were randomized into 4 groups, blank control group (did not burden [...]