Objective:The incidence of ovarian cancer is the third in the female reproductive system malignancies, and this trend is rising recently. The mortality is in the first place. Because of ovarian cancer’s onset and progress is conceal,70% patients are terminal when discovered with 30% of them have a 5-year survival rate. The main reasons of ovarian [...]
Background and objective:Primary hepatic carcinoma is mainly hepatocellular carcinoma (HCC). It is a common clinical tumor with high malignancy and fatality rate. Its main biological characteristic is hadro-invasion, easy recurrence, metastasis and poor progosis. At present, there are many treatments of HCC, such as surgery, radiotherapy, chemotherapy and other kinds of treatments. Because of their [...]
BackgroundBreast cancer is the most frequently diagnosed cancer among women, the attack rate of it is the first place of all women cancer in developed countries in Europe and American, and only in American, breast cancer patients accounts for about 30 percent of all diagnosed cancer women. Although china belongs to lower incidence of breast [...]
Nasopharyngeal carcinoma(NPC) is one of the commonest carcinomas with a high degree of malignant Phenotype in Southern China.especially those of Cantonese origin. Both the geographic pattern and familial aggregation of incidence are two main characteristics of NPC. The carcinogenesis of nasopharyngeal epithelium is a multi-stage, multi-path and multi-mechanism process, which is involved in the effects [...]
Aim:To evaluate in vivo anti-hepatoma effect of arenobufagin and explore probable molecular mechanisms of arenobufagin-induced apoptosis in doxorubicin-sensitive and -resistant human hepatoma cells (HepG2 and HepG2/ADM), and further study inhibitory effect of arenobufagin on the invasion and migration of HepG2 cells. Methods:S180 sarcoma and H22 hepatoma animal model in KM mice, together with orthotopic transplantation [...]
Objective To study the effect of mangiferin on the growth inhibition and invasive ability of human lymphoma Raji cells.Methods Raji cells were given different concentrations of mangiferin. The inhibition ratio of the cells were measured by MTT assay and invasive ability were measured by Minicell chamber assay.Results The results of MTT assay showed that the [...]
Objective:To evaluate the effects of curcumin on proliferation, invasion and VEGF-C gene expression in Human breast cancer cell line MCF-7.To explore the molecular mechanism of the inhibitory effect of breast cancer metastasis by curcumin.Methods:1.Proliferation of MCF-7 cell inhibited by curcumin was assessed by MTT. IC50 value was calculated by drawing the growth curve.2.Invasion of MCF-7 [...]
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