1. Objectives and significanceWith development of society and improvement of people’s life standard,life-style changes, and aging of population, diabetes prevalence increased steadily in the world, which has become another serious public health hazard Chronic non-communicable diseases secondary only to the heart and cerebrovascular diseases, tumors.Diabetes is a lifelong disease and cannot be cured, with the [...]
Objective:To study the expression and its significance of HIF-1αprotein content and total gene during myocardial ischemia-reperfusion in dogs with cardiopulmonary bypassMethods:18 healthy dogs were randomly divided into three groups including control group (no aortic cross-clamping), model group and DMOG intervention group (aorta was blocked for 60 min in the latter two groups). Before bypass, while [...]
ObjectivePass to evolve a sociological survey, acquire first hand information and realize the serum lipid level and insulin resisted-level whose are or be older than 35-year-old dweller of. I advance to analyze the correlation of their serum lipid level and their insulin resisted-level and inquiry into the serum lipid index mark of predicting the insulin [...]
The Effect of Marine Collagen Peptide on the Glucosetrans Porter-4 of Muscle of Type 2 Diabetic Rats
Objective: By building type 2 diabetes mellitus (T2DM) rats model, this research aims to explore to observe the influence on the expression of GLUT4 of the muscle and the influence of MCP interentions. Methods: after one week of acclimation, 10 of the 40 six-week-old SPF male SD rats were randomly selected as normal group (NG) [...]
This thesis centers on the role of p38 Mitogen-activated protein kinase signaling pathways in inhibiting insulin resistance in myogenic IL-6. It investigates the changes of p38MAPK and the expression of IL-6 organizations and their function in improving or inhibiting the insulin resistance on rats with the intervention of sports and high-fat diet and the injection [...]
Artemisia sphaerocephala polysaccharide(ASP) is a polysaccharose substance from waste residue when Artemisia sphaerocephala Krasch. seeds are oil pressed, essential constituent of which is galactomannan, a linear macromolecule with many branched chains and it has been studied for well hypoglycemic effect and antioxidant activity. Sulfated derivatives of ASP(SASP), Phosphated derivatives of ASP(PASP) and Selenide of ASP(SeASP) [...]
Diabetes mellious(DM) belongs to Xiaoke in Traditional Chinese Medicine (TCM), and is caused by deficiency of vital energy and yin, According to xiaoke haemostasis theory, the principle of treatment is to supply supplemental qi and nourish yin, and to activate blood cir culation to dissipate blood stasis. Type 2 DM is a metabolic disorder causeded [...]
Objective:This study is to construct a short hairpin RNA(shRNA) eukaryotic expression vector targeting the IKKα/βgenes by RNA interference(RNAi) and to establish stable Human Umbilical Vein Endothelial Cells line (HUVECs) expressing IKKβgene.Methods:The nucleotide sequences of IKKα/βgenes were retrieved from Genbank. According to the guidelines for shRNA design, four pairs of DNA sequence containing a small hairpin [...]
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