Objective:To analyze and explore the efficacy and mechanism of improving non-alcoholic fatty liver disease insulin resistance by the method of invigorating spleen to reduce phlegm, based on clinical syndrome, hepatic function, blood lipids, fasting blood glucose and fasting insulin level.Method:60cases with non-alcoholic fatty liver disease who were accepted by strict standards according to the research [...]
Objective:Experimental study to explore of Xuezhikang for glucose and lipid metabolism, for insulin secretion and insulin sensitivity, and to study its possible mechanism. In order to play better Chinese medicine to improve the role of glycolipids in clinicalMethods:40male12weeks of age, clean level in db/db mice (congenital diabetic mice model),20weeks of age, littermates db/m mice(non-diabetic control [...]
ObjectiveTo investigate the influence of acupuncture on Leptin and FFA on weight loss, to explore the mechanism of losing weight by acupuncture and IR.Method50SD rats were fed with high fat diet to induce obesity in two months the other10rats were fed given a standard diet as controls. Body weights were measured at each weekend in [...]
Object iveTo reveal the mechanism of Modified Jiaotai Pills in treating type2diabetes mellitus by observe effect of Modified Jiaotai Pills on insulin resistance in type-2diabetic rats which used Modified Jiaotai Pills, in order to improve the level of prevention and treatment in type2diabetes mellitus Clinical efficacy of traditional Chinese medicine and pharmacy, and lay a [...]
Objective: To explore the relationship between uric acid（UA），diabetic nephropathy, blood lipid metabolism and insulinresistance.Methods: Chose95patients of type2diabetes as a case group anddivide them into three groups according to their UAER in24hours:32patients with normal urine protein (＜30mg/24h);45patients withmicroalbuminuria (30-299mg/24h);18patients with clinical albumin(≥300mg/24h). Set32with normal urine protein as the control group.The fasting glucose, glycosylated hemoglobin, UA, creatinine [...]
Background and purposeGlucose intolerance is frequently observed in patients with advanced liver cirrhosis and the patients suffer complications of cirrhosis more frequently as well as increased mortality. It is suggested that insulin resistance predominantly occurs in peripheral tissue and especially glucose uptake diminished in muscular tissue. However, to date, the underlying molecular mechanisms remain elusive. [...]
Objective:To investigate influences of Triterpenoids from Psidium Guajava Leaves (PGs)on the differentiation, proliferation, glucose uptake, FFA production, adiponectinsecretion of3T3-L1pre-adipocyte and its possible mechanism.Methods:3T3-L1pre-adipocyte was cultured in vitro. After adding Triterpenoids fromPsidium Guajava Leaves (PGs) PG-1, PG-3, PG-5, PG-7(1μM,3μM,10μM,30μM,100μM) and positive drug Rosiglitazone10μM and Sodium orthovanadate10μM tothe culture medium for48h, the cell viability was tested by [...]
Objective To investigate the change and significance of serum retinol binding protein4(RBP4)in timing of oral glucose tolerance test (OGTT) in patients with gestational diabetes mellitus(GDM).Methods From May2008to May2010,forty-five women with GDM and forty-five healthy pregnant women were included in24-28weeks at Women’s Hospital of Zhejiang University Medical College. The GDM was diagnosed based on National Diabetes [...]
Hello,My name is Jack,Ph.D. Supervisor, Welcome to My WebSite