PartⅠClinical and myopathological analysis of 34 cases with dermatomyositisBACKGROUND:Dermatomyositis is a systemic inflammatory disease involves both skeletal muscles and skin subsequently or simultaneously, which can onset in any age and shows higher incidence in females. According to clinical features, Dalakas divided dermatomyositis into three subgroups:①Most cases show progressive muscle weakness and typical skin lesion, which [...]
O-linkage ofβ-N-acetylglucosamine (O-GlcNAc), is a reversible and dynamic post-translational modification attached to serine or threonine residues. In contrast with typical glycosylation, O-GlcNAcylation modifies a wide variety of cytoplasmic and nuclear proteins. The addition of O-GlcNAc to proteins is catalyzed by O-GlcNAc transferase (OGT) and removal by O-GlcNAc–selective N-acetyl-β-D-glucosaminidase (O-GlcNAcase, OGA). This abundant post-translational modification, analogous [...]
Objective:To explore the significance of Ras family (H-ras/N-ras/K-ras) protein expression and gene mutation in skin pathological scar and scar carcinoma tissues.Methods:It is used that 16 cases skin pathological scar tissues and 20 cases skin scar carcinoma tissues to compare with 10 cases normal skin tissues. The expression of H-ras, N-ras and K-ras proteins were detected [...]
Part IExpression of Caspase-4 and Caspase-3 Gene Related Apoptosis in Sternocleidomastoid of Congenital Muscular Torticollis Shenzhen Children’s Hospital, Zunyi Medical College Wang Shuaiyin (Candidate of MD) Tang Shengping (Supervisor)Objeetive To detected protein expression of Caspase-4 and cleaved Caspase-3 in sternocleidomastoid of congenital muscular torticollis and to explore the possible mechanism of apoptosis in the pathogenesis [...]
Objective:The endometrium, lining of the uterus, is a highly active organ that is periodically remodeled during the lifespan. Many literatures have demonstrated that the presence of an adult stem cell (ASC) population in this tissue because of its cyclic regenerative capacity. In this study, we aim at (1) identifying and localizing the putative ASC population [...]
【Objective】To observe the ultructure of articular cartilage and change of typeⅡcollogen after blunt injury, to investgate the etiopathogenesis of traumatic osteoarthritis.[Materials and methods] The different cartilage injury models of the femoral trochlea of rabbit in vivo was made by impacting of different times.24 New Zealand adult rabbits were divided randomly into 20 times and 40 [...]
Objective To investigate the expressions of HMGB1 and RAGE in AAA and the role they play in the development and rupture of AAA.Methods The protein expression of HMGB1 and RAGE in 42 specimens of AAA and 10 specimens of normal abdominal aorta tissue were measured by immunohistochemistry. The 42 specimens of AAA contained 9 cases [...]
Objective To investigate the difference between the bile cast after liver transplantation and the bile stone through the technology of scanning electron microscope (SEM) and so on, in this foundation, we investigate the bile cast’s histochemistry and immune cells by the method of immunohistochemistry. Lay the foundation for the further study of bile cast after [...]
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