Objective: To analyze the levels of CD4~+CD25~+FoxP3~+T cells、IL-10、eosinophileand basophile in the blood of children younger than three years with acute lowerrespiratory tract infection (LRTI) with different clinical features. To assess theseimmunological status in patients with wheezy LRTI, to explore the correlation between thewheezy LRTI and asthma.Methods:113steroid-na ve patients with LRTI were enrolled，19healthy donorswere also enrolled [...]
Objective:CD4+CD25+regulatory T cells which is a group of full-time immune suppression cells, are participate in process of immune tolerance, inhibit organism antitumor immunity. And there are numerous studies have shown that the numbers of Treg are higher in leukemia and a variety of malignant tumor patients, are negatively correlated with tumor the cure effect, prognosis [...]
Objective To investigate the effects of Chaihushengshitang on IL-10and VEGF in Serum and BALF of Asthmatic Rats and explore the mechanism of treating asthma with Chaihushengshitang.Methods Eighty-four male Wistar rats were divided randomly into seven groups: normal control group,model control group,dexamethasone group,dingchuantang group, chaihushengshitang low dose group,chaihushengshitang middle dose group chaihushengshitang high dose group,each group [...]
ObjectivesThe aim of this study is to explore the relationship between serum uric acid(SUA) and development or activities of central nervous system infections (CNSI),which may be helpful to provide new ways for condition assessment and clinicalintervention of CNSI.MethodsThe SUA levels were measured in357patients with different types of CNSI(bacterial meningitis or meningoencephalitis, viral meningitis or meningoencephalitis, [...]
Objective To investigate the expression of Interleukin-6(IL-6) and Interleukin-10(IL-10) in Aspergillus fumigatus keratitis in corneal epithelial cells of rats, and analysis the effect on anti-fungus immunity.Methods72Wistar rats were divided into2sections at random, including Group A1、B1、C1(6rats in each group) and Group A2-. B2、C2(6rats in Group A2and24rats in Group B2C2). Group Aland A2was blank control group. Group [...]
Background and Objiective:Probiotics have shown beneficial effects in the treatment of Helicobacter pylori infection; however, the mechanisms behind such effects are not fully understood. In this study, we have investigated the immunomodulatory effects of probiotics in a mouse model of H. pylori infection.:To evaluate the therapeutic efficacy of probiotics for H.pylori-related gastritis in C57BL/6mouse model [...]
Objective：to detect the expression levels of Th17cells and Treg cells in colon cancertumor tissues of patients and the expression levels of related cytokines in the peripheralblood, analysis of Th17/Treg in patients with colon cancer changes, observe therelationship with its clinical and pathological tissue typing, and discussed the relationshipwith the tumor occurrence and development and its [...]
Objective:To investgate the effect of Bushen Shugan(BSSG) formula on immune function and endocrine system of lewis lung cancer mice and the effect of serum containing BSSG on the proliferation of A549cells and discuss the possible underlying mechanism.Methods:In Vitro Experiment.30healthy SD mice were randomly divided into five groups:model control group、DDP group、low-dose group、middle-dose group、 high-dose group of [...]
Object This study was designed to investigate the mechanism of Berberine ameliorate the pathological physiology of heart failure in a model of chronic heart failure through the observe of serum tumor necrosis factor-a(TNF-a), interleukin-1(IL-1), interleukin-6(IL-6), interleukin-10(IL-10) and myocyte inducible nitric oxide synthase(iNOS) gene expression.Method The Sprague-Dawley(SD) rat of experimental heart failure (HF) model were established [...]
Objective:Th9cells is a new subset of T helper cells, it’s mainly excrete IL-9and IL-10. IL-9and IL-10were believed to be related to the many diseases, especially with respiratory inflammatory diseases, like asthma. The aim of this research is to investigated the distributing of eosinophils (EOS), the expression of IL-9and IL-10in chronic rhino-sinusitis and fungal rhino-sinusitis and [...]
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