BackgroundOrthodontic tooth movement is induced by mechanical stimuli, which is not only a simple mechanical shift, but also a process of the periodontal tissues remodeling, especially the alveolar bone. The forces applied to the teeth are transmitted through the periodontal ligament (PDL) to the supporting alveolar bone, leading to bone deposition on the tension side [...]
Objective:To investigate the immunological effects of human periodontal ligament stem cells(hPDLSCs) on NO expression in lipopolysaccharides(LPS)/and L-NMMA.Methods:Fifty health premolars from patients between 12 to 18 years old were extracted for orthodontic reasons, periodontal tissues were isolated and cultured in vitro to obtain hPDLSCs. Cells in 4th-8th passage cells were used for the following experiment. Several [...]
IntroductionThe periodontal ligament functions as a cushion to mitigate the mechanical forces of mastication and maintains homeostasis such as remodeling of the adjacent bone. Periodontal ligament retains regenerative capacity to some degrees throughout adulthood, which is attributed to stem cells maintaining their proliferation and differentiation potential in the area. Previous studies have determined that periodontal [...]
The effect of insulin-like growth factor I on oesteogenesis of human periodontal ligament stem cells under simulated microgravityThe deficiency of periodontal tissue caused by periodontitis is the main cause of tooth missing in adults. Tissue engineering aims at constructing such tissues with physiological structure and functions in vitro, however the effect of gravity influenced the [...]
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