Objective:1.Investigate the resistivity of Hp of gastric mucous membrane of patients with upper gastrointestinal disease to three commonly used antibiotics(metronidazole, charithromycin, amoxicillin), screen out resistant strains.2.To explore the inhibiting effects of total alkaloids of sophora alopecuroides (TASA),and monomer alkaloids(matrine,oxymatrine,and sophoridine)in vitro. Explore the feasibility of the therapy of Hp infection.Methods:1.To collect the specimens with rapid [...]
Background and Objective: Helicobacter pylori (Helicobacter pylori Hp) has a veryclose contact with a variety of upper gastrointestinal diseases,and is a risk factor for pepticulcer and chronic gastritis, Helicobacter pylori is closely related with non-ulcer dyspepsia、gastric cancer and gastric mucosalymphoid tissue lymphoma’s the occurrence anddevelopment, in1994the world Health Organization as a class Ⅰ carcinogen.Helicobacter pylori [...]
Objective:To investigate the expression of Notch1,Jagged1,COX-2and Snail in gastric cancer as well as their correlations with the clinical pathology and helicobacter pylori infection.Methods:The expression of Notch1, Jagged1,COX-2and Snail proteins were detected in60cases of gastric carcinoma,60cases of normal gastric mucosa tissue and20cases of normal gastric tissue by tissue micmarray technique and immunohistochemical staining. For detection of [...]
Purpose：Research the clinical effects of Henoch-Sch nlein purpura（HSP）treated by anti-helicobacter pylori.Data and Methods：Choose128children who had Henoch-Sch nleinpurpura and had been treated in the China–Japan union hospital of JilinUniversity from2000.Jan to2012.Jan. Clinical performances are feel sick、vomit、bellyache、diarrhea、hematochezia. Blood helicobacter pylori detectionand gastroscope detection are used to check HP. We got88children whoseresults of these two detections are positive, [...]
Objectives:To study the preventive and therapeutic effects of chlorophyll-carotene paste from pine needles on experiment gastric ulcer, in order to provide theoretical and experimental evidence for further exploitation of the medicinal value of the pine needles.Methods:(1) The safety of the active fraction was evaluated elementarily by acute toxicity test in mice.(2) Rats were divided randomly [...]
Objective:To observe the clinical effect of Modified Chaihu Shugan powder combined with Helicobacter pylori(H.pylori, Hp) eradication therpy on treating H.pylori associated chronic gastritis of liver stomach disharmony TCM syndrome type, analyze the clinical symptoms, the gastroscopy and the pathological examination, explore the curative effect of traditional Chinese medicine combined with western medicine treatment.Methods:According to the [...]
Aims This study aimed to investigate the effect of the ancestral origin of Hp on the development of gastric cancer through analyzing the genetic clustering of Helicobacter pylori (Hp) strains from gastric cancer and the chromosome damage by different Hp isolates.Methods43Hp strains were isolated (21with gastric cancer) from gastric biopsies. Their virulence genotypes were determined [...]
AIM:To observe the intervention effect of niweikang in rats with chronic atrophic gastritis.METHODS:A rat model of chronic atrophic gastritis was established by infection of Helicobacter pylori and intragastric infusion of Sodium Salicylate and alcoho1.65 Male Wistar rats were randomly divided into 4 groups:the normal control group, the model group, the niweikang intervention group and the [...]
Objective:To investigate the expression of RUNX3and DNMT1in human gastric cancer, and to find out the clinical significance and the effect of Helicobacter pylori (HP) infection.Methods:Reverse Transcriptase-Polymerase Chain Reaction(RT-PCR) and immunohistochemical method were used to detect mRNA and protein expression of RUNX3and DNMT1in70cases of primary gastric carcinoma and70paired adjacent marginal normal gastric carcinoma tissues from surgery.Results:The [...]
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