Objective:To investigate pharmacokinetics of Tet eye drops by high-pressure liquid chromatography(HPLC).And to provide basis to prevent Haze after refractive operation in clinic.Methods:Eighteen New Zealand rabbits were divided into nine groups in random.There were two animals in each group.one 50ul drop was instilled in the eyes of rabbits in each group.Lacrimal fluid,Cornea,Aqueous humor,Iris-ciliary,Lens,Vitreous were obtained at [...]
Objective: Observe and compare the cornea epidermis haze develop-ment after Epi-LASIK and Flap-free Epi-LASIK operation, and preliminary probe into its pathogenesis.Methods: 21 heathy New Zealand big-eared rabbits, 18 of them are performed Flap-free Epi-LASIK and Epi-LASIK operation respectively on each eye. Then do -10D cutting with VISX20/20 . The other 3 rabbits are use to [...]
Corneal is an important transparent tissue occupying the anterior pole of the globe. The injury because of mechanical injury, operation and chemical burn are very common in superficial injury of eye. The processes of wound healing and scarring are essential means by which the body maintains its structural integrity, but tissue repair in and around [...]
Part one: Features associated with occurrence of subepithelial corneal Haze after laser subepithelial keratomileusisObjective: To explore factors which lead to occurrence of subepithelial corneal Haze after laser subepithelial keratomileusis (LASEK).Methods: LASEK was performed on 202 eyes of 106 patients between Jan, 2006 and Jun, 2006 in our hospital. The patient data were evaluated retrospectively included [...]
Objective To study the changes of corneal I precollagen on rats by Excimer Laser surgery. After comparing the difference of I precollagen content between non-operation area, transparent cornea area and haze area, the time content curve should be made. Making the correlation analysis of the haze area’s area and the degree and the precollagen content [...]
Objective We trickled the amniotic extraction on the ocular surface of the rabbit corneas after the excimer laser photorefractive keratectomy in order to discuss the effect and mechanism of the amniotic extraction on the healing of the corneal wound and explore a new way to reduce the haze after PRK.Method Eighteen New Zealand healthy white [...]
Objective:Observe the inhibitory action that Matrine forms after rabbit eye PRK to Haze and discuss the effect that Matrine has on the expression of Collagen﹑TGF-β1﹑a-SMA in rabbit coneas.Method:There are health no eye disease’s New Zealand white rabbits 63, under the same conditions, manufacturing PRK animal model. After the technique, rabbits were randomly divided into 1%Matrine [...]
Part one The study of matrine effect on postoperative early stage apoptosis of rabbit and the expression of NF-κB after PRKObjective:To study the effect of matrine about early using,and explore whether it can inhibit the startup factors of haze(wound healing and apoptosis).Methods:Twenty-four healthy new zealand rabbits were randomly distributed into four groups:control group(drop NS preoperative [...]
Objective: To evaluate the feasibility of mitomycin c (MMC) in preventing Haze and the stability of visual functional state after laser epithelial keratomileusis (LASEK ) surgery of moderate myopia.Methods: The study was taken in 36 eyes of moderate myopia patients received LASEK. Eyes were divided into 19 eyes of conventional LASEK (control group) and 17 [...]
There has been a renewed interest in surface ablation modalities like epipolis laser in situ keratomileusis (Epi-LASIK) over the past few years to avoid laser in situ keratomileusis (LASIK)-related complications, such as ectasia and dry eyes, and flap-related complications. However, the development of corneal Haze is an important factor to restrict the corneal surface refractive [...]
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