Objective: Rabbit Müller cells are isolated and cultured in DMEM/F12 with different concentrations of glucose and insulin, just simulating hyperglycemia and hyper-insulinemia. Through periodic acid-Schiff(PAS) assay, immunofluorescence technique ,analyse the localization and semi-quantitative of glycogen, glycogen synzyme(GS) and glucose transportation protein-1(GLUT-1) in the rabbit retinal Müller cells, to observe the effect of hyperglycemia and hyper-insulinemia [...]
Objective:By the study of the percentage of different types on diaphragmatic muscle fibre and the change of the glycogen content on acquired pectus excavatum in rats, we want to investigate the influence of the deformity of pectus excavatum on the diaphragmatic muscle function, so to provide theoretical basis with the further mechanism study of the [...]
ObjectivePlateau has a great influence on the organisms, mainly due to high altitude hypoxia and cellular energy disorder induced by hypoxia. It’s critical to maintain cellular energy balance for the compensatory adaptive response after exposed to hypoxia. Previous study shows that, AMP-activated protein kinase (AMPK) is a cellular energy detector, which closely monitoring the cellular [...]
Change of Glucogen in Detrusor of Rats with Partial Bladder Outlet Obstruction and Their Implication
Objective:To explore the change of glucogen in detrusor of rats with partial bladder outlet obstruction(PBOO) and their implication.Materials and Methods:A PBOO rat model was created,a control group had a sham operation for comparison.Individual urodynamic data were obtained weekly,then were killed at different levels of bladder dysfunction.Bladder sections were stained with Periodic Acid-Schiff(PAS) to assess overall [...]
ObjectiveThe objective of this study was to explore the mechanisms of Interlukin-6(IL-6) influencing the glucose metabolism and the expression of the insulin-sensitive glucose transporter 4(GLUT4) in skeletal muscle of type-2 diabetic rat model.MethodsThirty-six healthy male Sprague Dawley(SD) rats were randomly divided into 4 groups:group N was control rats with routine diets(n=10);group A,B and C were [...]
Background:Excess of ethanol consumption has been a serious social problem and ethanol is the most abused drugs used at present.Epidemiological data showed that excess ethanol consumption may cause many diseases such as ethanolic hepatitis and fatty liver.Also,ethanol disturbs the metabolism of carbohydrate,fat and protein.Because of the importance of homeostasis of blood sugar,more and more researches [...]
Pinctada martensii is one of the primary seashells of marine pearl cultivation in the southern china. It is fruitful and widely distributed in Guangdong, Guangxi, Hainan, Taiwan and so on. Pinctada martensii has abundant proteins, glycogen, essential amino-acid, varied vitamin, the minerals with particularities effects in physiology, such as zinc and selenium,and some physiological active [...]
Cardiovascular adaptation to long-term weightlessness is one of the fundamental questions concerned in the field of gravitational physiology over the next decades. The information generated will be helpful to develop adequate measures that improve the health, safety, comfort and performance for prolonged missions and enhance the postflight recovery of the cardiovascular function. Additional benefits will [...]
Adenosine, an endogenous nucleoside, is an important metabolite intermediate and exerts widespread regulatoiy and control throughout the body by interacting with specific cell-surface adenosine receptors. It is said that adenosine possesses marked cardioprotective properties, but the mechanisms for this beneficial effect are unclear. The role of adenosine in cardiac energy metabolism as a homeostatic metabolite [...]
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