Backgrand: Chondrocyte is the most basic anatomical structure of articular cartilage, andthe extracellular matrix (ECM) together constitute the articular cartilage. However, with theapplication of a dissecting microscope and the more in-depth study of articular cartilage, it wassuggested that the concept of the chondron, it is consist of one or more beaded cell shapewrapped around a [...]
As one of the most common hematologic malignancies, malignant lymphoma comprises a heterogeneous group which consisting of different clinicopathologic entities. Extranodal NK/T-cell lymphoma is a rare subtype of lymphoma, significantly different from other types of lymphoma, the histological features of this disease are angiodestruction, massive necrosis and apoptosis. Although most of the cases initially present [...]
Objective:To investigate the expression of embryonic stem cells key transcription factor Nanog in ovarian cancer and cancer stem cells.Methods:Reverse transcription polymerase chain reaction (RT-PCR) and immunohistochemistry were performed to detect the expression of Nanog gene in 10 cases of normal ovaries,10 cases of benign ovarian tumors and 60 cases of ovarian cancer. Ovarian caner stem [...]
Background & Objective：It has been proved that just a few days spaceflight can causemuscle atrophy. MGF can promote activation and proliferation of satellite cells in the muscletissue to prevent muscle atrophy. The expression of MGF under conditions of weightlessnessand its regulated mechanism under mechanical stimulation remain unclear. In the experiment,the expression of MGF in rat [...]
Background Gene therapy is emerging as a potential important treatment option ofcardiovascular diseases. However, progress in the field of gene therapy for cardiovasculardisease has been modest; one of the key reasons for this limited progress is the lack of genedelivery systems for localizing gene therapy to specific sites to optimize transgeneexpression and efficacy.Mesenchymal stem cell [...]
【Background】Gastric cancer is one of the most common malignant tumors, with lower mortality thanlung cancer and liver cancer in China. The gastric cancer patients were increased bymillions each year in the world, of which41%occurred in China. There were about35%people died of gastric cancer each year in china. Gastric cancer invading the serosa, lymphnode metastasis and [...]
Objective To explore the relationship between gene P21and P53expression and single nucleotide polymorphism(SNP) and the hepatocellular carcinoma (HCC)Methods The research was designed as a case-control study based on hospital. Reverse Transcription Polymerase Chain Reaction (RT-PCR) was used to measure the expression level of P21and P53in100cases of HCC and100cases of not-tumor patient, Genotypes of P213′UTR C/T [...]
This paper discusses in detail the beeswax as raw materials preparation andpurification of twenty-eight alkanol process, and then carry out the process of theoptimization; At the second, Octacosanol for the physiologic function of SD rats andSD rats blood biochemical parameters, hormone secretion followed by SD rats as theexperimental model ; Finally, by the molecular biology [...]
Objective：To investigate P53, Bax and Bcl-2and other apoptosis-related gene expressionchanges of ovarian cancer cisplatin-resistant cell lines SKOV-3/DDP after treated byallicin, and explore the mechanism of induction of apoptosis of tumor cells.Methods：The SKOV-3/DDP cell were randomly divided into control group, allicingroup(40ug/ml), cisplatin group(40ug/ml) and allicin(40ug/ml)+cisplatinum(40ug/ml)group. Each group were cultured24h,48h. We used MTT method to calculateproliferation inhibition [...]
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