Objective:To investigate the characteristics and differences of gastric cancer between old patients and young patients in the clinical manifestation, treatment and prognosis。Methods:Retrospective analysis was conducted on the clinical data from Jan. 2006 to Dec.2008 in Shandong provincial hospital recorded for 62 patients under the age o f 60 and 59 patients over the age o [...]
Objective:To explore the correlation of the expression between Gas-17 and TFFs in gastric cancer and the effects of gastrin on cell proliferation and the expression of in gastric cancer cells.Methods:The expressions of Gas-17、TFF1、TFF2 and TFF3 were determined by immunohistochemical method in 120 gastric specimens including 30 cases of normal gastric mucosa,30 cases of intestinal metaplasia,30 [...]
BackgroundClinical nutrition support has developed along with the needs of modern therapey,and its application has been very extensive at present. Most of the patients wih cancer exist different degree of malnutrit,and it is particularly important to give perioperative nutrition support in these patients with gastric cancer, Perioperative reasonable nutrition support can effectively improve the clinical [...]
Objective:The expression of secretend protein acidic and rich in eysteine (SPARC), E-cadherin and the zinc finger transcription factor Snail were detected in nonneoplastic mucosa tissue and gastric carcinoma tissue and discussed the relationship among them. Further research was used to find the relationship between their expression and the invasion, metastasis and prognosis of gastric carcinoma.Methods:①To [...]
Background:The immune status of patients with gastric cancer in the early postoperative period is instability. Up to date, there is few relative research about the assess of immunity in the early postoperative period. Moreover, there is no report about the intervene in the window period with adoptive immunotherapy.Objective:To assess the lymphocyte count, cell immune function [...]
Gastric cancer is one of the most common disease of malignant tumors which are harmful to health.Surgical resection and postoperative chemotherapy are the main methods to treat this disease for decades.Previous studies proved that angiogenesis play important role in gastric cancer development and metastasis.Recently,angiogenesis inhibitors have become the focus of tumor treatment,and some agents are [...]
Background:This study examined single nucleotide polymorphisms in IL-1βand PSCA and their associations with risk of developing gastric cancer in relation to Helicobacter pylori infection in Chinese Han population.Methods:We conducted a hospital-based case-control study including 221 incident gastric cancer patients and 190 gastritis controls. Serum levels of anti-H.pylori IgG were measured by enzyme-linked immunosorbent assay to [...]
Objective:To analysis the risk factors of complication of gastric cancer, and make a statistical analysis. To find out the major causes of Postoperative complication gastric cancer.Methods:We performed a retrospective analysis of 289 patients with gastric cancer from 2005 to 2009 in YanBian University Hospital. Meanwhile, to investigate the preoperative conditions of patients, includes:age, gender, level [...]
【Objectives】To investigate the expression of Suv39H1(suppressor of variegation 3-9 homolog 1),and histone methylation of H3K9 and H3K4 in Gastric Carcinoma,we design a siRNA segment targeting Suv39H1 gene to study its effect on cell growth ,cell apoptosis and histone modification in gastric cancer MGC-803 cells line.【Methods】1.The expression of Suv39H1, histone methylation of H3K9 and H3K4 was [...]
【Objectives】To investigate the expression of Suv39H1(suppressor of variegation 3-9 homolog 1),and histone methylation of H3K9 and H3K4 in Gastric Carcinoma,we design a siRNA segment targeting Suv39H1 gene to study its effect on cell growth ,cell apoptosis and histone modification in gastric cancer MGC-803 cells line.【Methods】1.The expression of Suv39H1, histone methylation of H3K9 and H3K4 was [...]
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