Objective: To explore the expression and significance of TREM-1、2（triggering receptorexpressed on myeloid cells-1、2）of liver in the（non-alcoholic steatohepatitis, NASH）rats andgallstone patients.Methods: High-fat diet fed rats and intraperitoneally injected a certain amount of oxygentetracycline build NASH rats model.Selected fifty-four clean male SD rats, comfortableenvironment,free diet,divided into three groups after a week,eighteen every group.①controlgroup:normal diet,the volume of saline [...]
Objective: To study serum of endotoxin、tumor necrosis factor-α（TNF-α）and soluble Toll-like receptor4（sTLR4）in liver cirrhosis withHeaptorenal syndrome and its clinical significance.Methods:50liver cirrhosis patients were divided into two Groups：single liver cirrhosis and liver cirrhosis with hepatorenal syndrome，15healthy subjects as controls. Their endotoxin and TNF-α、sTLR4weretested by linilus lysate test, enzyme-linked immunosorbent assay （ELISA）separately.spss17.0Correlation analysis was maken between endotoxin andTNF-α、 [...]
Objectives:To detect the level of serum total protein, albumin, interleukin-6(IL-6), tumor necrosis factor-a (TNF-a) and endotoxin, to explore serum protein changes and its mechanism in acute craniocerebral trauma, in order to provide conference for clinical nutrition support and reducing secondary brain trauma.Object and method:65patients with craniocerebral trauma from January,2008to September,2011in our hospital were included in [...]
Part I:Relationship between intestinal barrier function of small intestinal mucosa and plasma endotoxin in chronic liver damage ratObjective:To establish the models of rats with chronic liver damage.To explore the morphological structure changes of small intestinal mucosa and plasma endotoxin in rats with chronic liver;and explore its pathogenesis by examining and comparing the distribution and quantity [...]
Objective Mostly severe patients are complicated by nutritional and metabolic disorders, and the body is in stress and high metabolic conditions. Nutritional support is a necessary condition for successful rehabilitation, there are many methods of nutritional support, but enteral nutrition support is mostly conform to the body’s physiological and nutritional needs. But there were a [...]
Continuous renal replacement therapy is a common treatment in intensive care unit. The technique of CRRT has found increasing applicability in the treatment of patients with renal failure combined with cardiovascular instability, severe fluid overload, cerebral edema or hypercatabolism. With the development of the technology of CRRT, CRRT application category has extended from ARF to [...]
ObjectiveEndotoxemia is a high mortality disease, which induced by infection, serious burn or wound, can lead to septic shock, DIC, MODS, MOF, even lead to death. But there are currently no effective and safety anti-sepsis drugs in clinical use. HJM is a Chinese herbal preparation, which composed of scutellaria baicalensis, honeysuckle, moutan bark, and so [...]
【Objective】To investigate the influence of endotoxin on ERK1/2pathway of primary HSCs invitro.【Methods】HSCs were isolated from rats liver by the method of pronase E and IV collagenasedigestion and density gradient centrifugation. The cell viability was determined by Trypan blueexclusion staining. The purity of HSC was identified by the expression of desmin usingimmunocytochemistry SASC method. After3days normal [...]
Background:Breast cancer is one of the most common female malignant tumors. And more than1.2million women are diagnosed with breast cancer worldwide each year. Though breast cancer had once been considered largely as an illness of the Western word, it is a rising scourge in developing nations. In China, with the improvement of living standards, female [...]
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