Objective: To observe changes of clinical symptoms and signs as WOMAC and relevant serum cytokine of knee osteoarthritis (KOA)patients before and after treatment with electro-acupuncture and warm-acupuncture, to confirm the curative effects of electro-acupuncture and warm-acupuncture, to compare the disadvantage and advantage of the two treatments, to discuss the probable action mechanism of electro-acupuncture and [...]
ObjectiveChronic obstructive pulmonary diseases (COPD) is one of the most commoninflammatory disease of respiratory system. COPD has already become thepre-eminent heath problem worldwide, which mainly cause damage in lung and otherorgans at the same time. However, the detailed mechanisms of this disease are stillunclear. Recent studies have indicated that chronic inflammation is one ofrepresentative characters [...]
Objective There is increasing evidence that cancer cachexia patients have high cytokines levels, and bacterial translocation (BT) could increase cytokines secretion. The present study was to investigate association of bacterial translocation with cachexia and its impact on the outcome of patients with locally advanced gastric cancer.Methods From January2008to July2009, all of the consecutive patients with [...]
Section I Association of cytokine gene polymorphisms with long-term humoral response in children vaccinated against hepatitis B in infancyObjective To investigate the relationship between cytokine gene polymorphisms and long-term humoral response in children vaccinated against hepatitis B during infancy.Methods A total of293children (6.08±0.59years old) who received three doses of hepatitis B vaccine according to a0-,1-,6-month [...]
Objective:SOCS3was short for suppressor of cytokine signaling3,it played an important role in regulating organs injuries of diseases,and it could inhibite cytokines from releasing by feedback regulation of JAK/STAT signal path,however,there was no report about the role of SOCS3in inhibiting inflammation reaction in severe acute pancreatitis.We aimed to determine the expression of SOCS3in pancreas and lung [...]
With the development for technology, liver transplantation hasbecome the only definitive method of therapy for patients with end-stageliver diseases. However, the morbidity of ischemic-type biliary lesion(ITBL) after liver transplantation has kept in high level for long time. TheITBL seriously impacts survival rate and life quality of the recipientswith liver transplantation. Many specialists have been payed [...]
Backgrounds and objectivesSeptic shock, also known as endotoxic shock, is a syndrome caused by infection withpathogens and including mainly fever, shiver, cold clammy limbs, cyanosis, tachycardiaand the low blood pressure. It is a common clinical critical diseases with a high mortalityrate and often complicated by multiple organ dysfunction. It is the most common thatseptic shock [...]
Endophthalmitis is a severe complication of globe-penetrating injury. traumatic endophthalmitis develop fast and visual outcome is often frustrating. It is one of the most common diseases that frequently results in loss of vision. At present, the pathogenesis of traumatic endophthalmitis is not clear. Trauma not only change the normal structure and destroy the blood-retinal barriers [...]
1. BACKGROUNDAt the early stage following severe burn injury, there are violent changes happen withinternal environment. As results of trauma stress, direct damage by heat power and tissuehypoperfusion, inflammatory cells are activated such as mononuclear macrophage,neutrophils, lymphocyte, platelet, endotheliocyte, pro-inflammatory cytokines are alsoreleased increasingly. Vascular endothelial cells and leucocytes express more adhesionmolecules, which strengthen adhering [...]
AIM In this research,we will co-culture T lymphocytes from normal humans with MSCs which were isolated from Immune thrombocytopenia patients’s bone marrow, Umbilical cord and healthy people’s bone marrow.3days later, we will monitor the cytokines IL-2, IFN-y, IL-4and IL-10to illustrate the diffence of immunodulatory of three kinds of MSCs.Methods:Human bone marrow-derived MSCs were isolated by [...]
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