Background:Affective disorders in the elderly crowd in the high prevalence of a kind of mental disorders, and with pathy, loneliness and inferiority of depressive symptoms as outstanding performance. Patients often associated with anxiety, sleep disorder, suicide idea and physical discomfort. And these signs seriously affected the living and quality of life in the elderly population, [...]
Purpose: Carboxymethyl chitosan (CM-CTS) is a water soluble chitosan derivative by introducing–COOH groups to chitosan molecule and endows it some outstanding biological properties. CM-CTS has been a research focus in the field of pharmaceutical and biomedical industry for its unique physicochemical and biological properties such as biocompatibility, biodegradability, degradation controllability and antimicrobial activity. There have [...]
Objeetive:To study the effects and the mechanisms of Bushen Jiedu Huoxue Recipe for the Myelosuppression after Chemotherapy.Methods:140 Clean grade Kunming mices. half-female and half-male,Divided into two parts:preventive experiment and therapeutic experiment.Preventive experiment:Totally 60 healthy Kunming mice were used, half-female and half-male, randomly divided into 3 groups:normal control group, model group, Chinese herb Preventive group with [...]
Polysaccharide, as the natural high molecular compound, is a kind of Chinese traditional medicine active component. Many foreign scholars carry on researches by extracting plenty of polysaccharides from different creatures and it shows that the material has an effect on specific and non specific immune stimulation of body with a good immunocompetence. Polysaccharide works well [...]
Idiopathic pulmonary fibrosis (IPF) is a chronic and often fatal pulmonary disorder. Continued fibrosis leads to loss of lung function and ultimately death, Numerous factors have been implicated in this process, the molecular mechanisms of IPF are still controversial and elusive, but there are some signs show that fibroblast, proliferation, extracellular matrix deposition, and progressive [...]
Objective To investigate the role and mechanisms of metoprolol on the myocardial damage in rats with sepsis and to provide the theory for the treatment of sepsis.Methods 72 rats were randomly divided into control group(n=24), sepsis group (Cecal ligation and puncture was performed to induce sepsis, n=24) and treatment group (0.2mg/kg/h, n=24).The serum TNF-а, the [...]
Optimization of Extraction Process and Study of Immune Activity of Fomes Fomentarius Polysaccharides
Fomes fomentarius is a medicinal mushroom belonging to a family of Polyporaceae. The water extract of the fruiting body is usually used for the treatment of esophageal cancer, gastric cancer and uterine cancer. Studies indicated that the mushroom fruiting body containes phenols,organic acids,saccharides,polysaccharides and lactones.Current study of Fomes fomentariu is mainly focused on anti-tumor activity [...]
objectiveThe serum level of IL-7 were analysed by enzyme linked immunosorbent assay (ELISA). The correlations among parameters were analysed by spearman and partial correlation analysis. The aims of the study were to analysized the expression level of IL-7 in healthy subjects and patients with RA and to investigate the relationship between IL-7 and clinical characteristics, [...]
On the beginning of the theories of AD,which were the hypothesis of nerves immune inflammation and the hypothesis ofβ-amyloid protein cascades, and based on that the metabolic pathway of Aβparticipated in AD,The topic adopted Aβ1-40to inject the Hippocampus to induce neuronal damage in brain,to copy the AD rat model.By the curative target ofβ-amyloid protein deposition [...]
To study the effect of evodiamine on function regulation of dendritic cells (DC) and develop a new immunotherapy strategy of anti-inflammation. It has become a tendency to look for new anti-inflammatory drugs in Chinese traditional herbal medicine and to do new explorations and explanations for their pharmacological actions. Evodiamine, the major alkaloidal component isolated from [...]
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