ObjectiveAccording to the RNA interference can specifically block the expression of targeted genes,we design and construct small interfering RNA plasmid of chemokine receptor 4. The siRNA of CXCR4 plasmid is tansfected into SW626 cells, and to investigate the inhibitory effect of CXCR4 siRNA on the proliferation, invasion and metastasis capability of ovarian cancer cell SW626 [...]
Objective: To construct eukaryotic expression vectors of RNA interference specific for human CXCR4 and to detect the effect of recombinant retroviral vectors on CXCR4 mRNA in leukemia cell line (SHI-1) cells, the recombinant retroviral vectors lay the basis for the investigating the function of CXCR4 and searching a new gene therapy method of leukemia.Methods: The [...]
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