[Objectives] To compare the flavonoids content of Allium cepa extracted from water and ethanol, and the influence of the extractions on colorectal cancer cell proliferation、apoptosis and cycle.[Method] Allium cepa was extracted by water and ethanol, the flavonoids content of the extractions were detected by UV. Colorectal cancer cells(Lovo cells、SW480cells、HT-29cells、 HCT-8cells) were cultured in vitro, the [...]
Objective:In vitro studies of ginsenoside Rg3, sorafenib, oxaliplatin single agent and the joint impact on the growth of human hepatoma cell line, to find the best combinations and to explore its possible mechanism, in order to provide the basis for effective in the further animal experimental and clinical trials and ultimately to improve the clinical [...]
Objective:Nowadays, cancer is a serious hazard to human life and health of major diseases,its incidence increased year by year, so the cancer has attracted worldwide attention of the scientists,the study of cancer involves a lot of fields,for example:cancer etiology,the formation of grug resistance,metastasis,the killing effect of anti-cancer medicine on malignant tumor cell and so on. [...]
Background and purposeThe prevention and treatment of malignant tumor have become difficulty and key the scholars face as a result of the high incidence and mortality of cancer. The treatment of malignant tumor has experienced a long process. Surgical resection from extensive to the organization and function of the conservative therapy, have been developed to [...]
In the world, cancer Incidence and mortality rates showed an increasing trend. Cancerhas become the “killer” following the cardiovascular disease, which is a serious hazard tohuman health. Currently, the primary means for tumor treatment are surgery, chemotherapy,radiotherapy, biological therapy, endocrine therapy, Chinese medicine treatment,hyperthermia and radiofrequency ablation therapy and so on. As the tumor traditionaltreatment [...]
ObjectiveTo investigate the effect of LI-cadherin (CDH17) on the growth of human Hepatocarcinoma Cells,use small RNA technology down it’s expression in human Hepatocellular carcinoma cell line Hep3B and to explore the mechanisms.Methods1. SiRNA was transfected into Hep3B by Lipofectamine transfection method,using G418selection stable transfection of Hep3B-LI-cadherin-of SiRNA cell lines, and using fluorescence microscopy to observe [...]
Objective:By observe the anti-rumor effects as well as the cell cycle, the expression of β-catenin andcell cycle reglation factor cyclinD1on the Lewis lung cancer, to explore the inhibitionmechanism of Compound Guizhu Capsule (CGZC) from the perspective of signaling patheway,so as to provide an objective experimental foundation for the development and clinicalapplication of CGZC.Methods:Established the mice [...]
Breast cancer is one of the most common malignant tumors in women. Whetherin developed or developing countries, the incidence and mortality rates of breastcancer are relatively high. The causes of breast cancer are quite complex, in additionto genetic factors, high-fat diet, obesity, hormones, immune, and variousenvironmental factors (physical and chemical, biological factors and lifestyle, etc.)may [...]
Ovarian cancer is the highest mortality rates malignancy in woman. Platinum-based combination chemotherapy is a standard treatment for ovarian cancer, but the5-year survival of advanced-stage ovarian cancers remains below in the thirty percent,primarily due to the rapid development of resistance. So a new method which is usedfor reversing drug-resistant tumor has become an important issue.Studies [...]
Esophageal cancer is the common disease in our country, which affects thepublic health. Currently the recommended therapy of curing this cancer is thecombination of radiation, chemotherapy and operation. To enhance theradiosensitivity of the cancer cell is one of the most important ways to improve theeffects of radiotherapy. The irradiation can cause the G2phase arrest, offering [...]
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