OBJECTIVE:To investigate the mechanisms of radiation-induced lung injury based on vascular endothelial cell injury.METHODS AND MATERIALS:Wistar 75 rats were irradiated to the right hemithorax with a single dose of OGy,7.0Gy,14.4Gy. Serial studies were performed before and 1,7,30,90,180 days after irradiation. Histological studies were carried out to detect histological changes in the pulmonary after irradiation. Immunohistochemistry [...]
Objective: To investigate the expression of MMP-2, VEGF, CD105 and Ki67 in human small cell lung cancer tissues, normal lung tissues and the correlation of the four indicators, and analyze the relationship between the biological characteristics and prognosis. It will provide theoretical basis for the clinical treatment and prognosis in SCLC.Methods: Immunohistochemistry SP method was [...]
Objective:To evaluate the immunohistochemical expression of integrinαvβ5(INTαvβ5) in cervical cancer, and reveal the relevance between integrin avP5 and the angiogenesis of cervical carcinoma.Methods:In 15 normal cervical epithelia (NCE) cases,15 cervical carcinoma in situ (CIS) cases and 60 invasive cervical carcinoma (ICC) cases, immunohistochemical PV 2-step method was used to examine the expression levels of INTαvβ5 [...]
Background and objectiveThe endometrium cancer refers primary in an endometrium group of epidermis malignant tumor.It is also known as uterine cancer, more common in postmenopausal women, high age 55-65 years, and most patients with obesity, hypertension, diabetes triad. In recent years, as women live longer and procreate with the concept of change and post-menopausal estrogen [...]
Laryngeal squamous cell carcinoma is one of common malignant tumors in head and neck,95%-98% of Laryngeal cancer is squamous cell carcinoma. Whose therapy is mainly radical surgery combined with radiotherapy or precise radiotherapy, patients in early stage may obtain better local control rate, but metastasis can not be prevented or reduced, for sufferer in middle [...]
Cancer is one of the diseases that serious threat to human health, so far, had not yet been found satisfactory management method. thus seeking new antitumor method is particularly important. Infiltration and metastasis are not only the major characteristic of the malignant tumor, but also the key to its hard curing and the resulting death [...]
Objective: To investigate the expression of CD105 in endometriosis for exploring the role of CD105 in the pathogenesis of endometriosis.Methods: Immunohistochemistry and RT-PCR were used to detect the expression of CD105 in the eutopic and ectopic endometrium from 40 cases with endometriosis (eutopic endometrium group and ectopic endometrium group ) and in the normal endometrium [...]
Background: Angiogenesis is one of the mechanisms most important for the postoperative recurrence and metastasis of hepatocellular carcinoma (HCC). Thus, finding the molecular markers associated with angiogenesis may help to identify patients at increased risk for recurrence and metastasis of HCC. This study was designed to investigate whether CD105 or CD34 could serve as a [...]
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