Periodontitis is a chronic inflammation of the gingiva and periodontal support tissueit is one of the main cause of tooth loss. The onset and progress of periodontitis is mainlyaffected by bacteria and other environmental factors and regulation. Recently, there issufficient evidence that the gene plays an important role in the onset and progression of thedisease.In [...]

Objective:To investigate the relationship of plasma levels of calcitonin gene-related peptide and neuropeptide Y with extent of coronary atherosclerosis,according to the calcitonin gene-related peptide and neuropeptide Y concentration of coronary artery disease group and normal group which divided by coronary angiography.Method:112cases were selected in hospital,who were for three generations of yunnan’s living for a long [...]

Objective:To investigate the correlation of blood calcitonin gene-related peptide(CGRP), substance P(SP) and heart rate variability with the severity of coronary atherosclerosis.Method:A total of 172 patients were randomly selected who attended the cardiovascular department in the first affiliated hospital of Zhejiang university medical college. The CHD patients included cases with single vascular lesions(n=54), two vascular lesions [...]

BACKGROUND: An accelerated speed of fracture-healing in patients with traumatic brain injury (TBI) is often encountered in our clinical practice. However the mechanisms responsible for this phenomenon are remain unclear. After TBI, many cytokines or peptides has been reported change their expressions, suggest that the phenomenon of accelerated speed of fracture-healing may be associated with [...]

Objective: To investigate the Xinjiang Uygur and Han plasma levels of calcitonin gene-related peptide and cerebral infarction (CI) of the relationship. Methods: The ELISA method, the Xinjiang region of 126 cases of ischemic stroke patients and 108 patients with associated age, gender matched controls plasma calcitonin gene-related peptide (CGRP) levels. Cerebral infarction and one Uighur [...]

BACKGROUNDDespite the progress that has been made in bone regeneration, fracture caused by trauma infection and a variety of reasons and Bone nonunion still represent the medical and socioeconomic challenge.In order to improve the treatment outcome fundamentally, clarify the pathophysiology and molecular mechanisms of bone formation reconstruction and remodeling are the base and starting point. [...]

BACKGROUNDDespite the progress that has been made in bone regeneration, fracture caused by trauma infection and a variety of reasons and Bone nonunion still represent the medical and socioeconomic challenge.In order to improve the treatment outcome fundamentally, clarify the pathophysiology and molecular mechanisms of bone formation reconstruction and remodeling are the base and starting point. [...]

Mas-related G protein-coupled receptors (Mrg receptor) is uniquely located in the small diameter neurons in dorsal root ganglia (DRG) and trigeminal ganglia (TG), suggesting that these receptors are involved in nociceptive information processing or opioid analgesia. Previous studies in our laboratory have demonstrated that activation of rMrgC modulates the development of morphine tolerance.The present study [...]

BACKGROUNDHypertension is a common disease that impacts human health. It may cause tissue injury such as heart, kidney, brain and artery. Cardiovascular remodeling is the most important adaptation response. Cardiac remodeling includes cardiomyocyte hypertrophy, apoptosis and myocardial fibrosis, which may cause cardiac functional decompensation and ultimately results in heart failure. Vascular remodeling is structure and [...]

Objective:observe the changes of plasma content of endothelin and calcitonin gene-related peptide in embolization of intracranial aneurysms under intravenous anesthesia and the influence of continuous infusion Nimotong on endothelin and calcitonin gene-related peptide.Methods:32 patients undering selective embolization of intracranial aneurysms were randomly divided into two groups, nimotong group (N) and control group (C).After anesthesia induction, [...]