Object:To Observe the effects of Anastrozole and Tamoxifen on the liver function in postmenopausal women with breast cancerMethods:There are14postmenopausal women with breast cancer who underwent adjuvant endocrine therapy. They were treated with oral Anastrozole (n=7) or oral Tamoxifen (n=7).We test and analyze the liver function in3years, using ALT, AST, TBIL, GGT and AKP, before and [...]
ObjectiveTo observe the distinguish pathologic expression and clinical characteristics and explore the prognosis and prognostic factors of basal like breast cancer by studing the data of48basal like breast cancer and198non-basal like breast cancer.Methods246female patients with newly diagnosis of infiltrating ductal breast carcinoma from Jan2006to Oct2008in Qingdao Municipal Hospital were analysed retrospectively. By observing the special [...]
Objective To discuss the clinical and prognostic significance of CCND1 and MDM2 proteinexpressions in breast cancer.Methods The CCND1 and MDM2 proteins in 59 breast tumor tissues and 19 normal breasttissues were detected by immunohistochemistry. The relationship between the expressions ofCCND1 and MDM2 and clinicpathological features of breast cancer were analyzed.Results In the tissues of breast [...]
Objective:To investigate the distribution of breast cancer patients with newly diagnosed, explore the relationship between the Body Constitutional Type in TCM and the Syndromes of breast cancer, find the law of the distinction and treatment, combine the “distinguish syndrome for treatment” and “distinguishconstitution for treatment” in order to use it in clinical diagnosis and treatment.Methods:Collect200cases [...]
Object ivesObserving the effect of Tao Hong Si Wu Decoction to the VEGF signaling pathways and their receptor in women with breast cancer, and exploring the impact on the tumor angiogenesis, tumor lymphagenesis, the VEGF signaling pathways of Tao Hong Si Wu Decoction.Methods40cases met the inclusion criteria were randomly divided into2groups. Treatment group, of20cases:Tao Hong [...]
BackgroundsRadiotherapy is a commonly used method of breast cancer comprehensive treatments. However, it can cause a series of local and systemic adverse reactions, which seriously influence the quality of life. The period of radiotherapy is defined as periods from the beginning to one week after radiotherapy [1]. The advantages of Chinese medicine treatment can improve [...]
Object iveThe objective of the subject is to observe the effect of the kidney nourishing therapy on the estrogen level of menopausal breast cancer patients taking Aromatase Inhibitors.Methods32cases met the inclusion criteria were randomly divided into2groups: the treatment group (16cases) taking traditional Chinese kidney-nourishing medicine, Aromatase Inhibitors and calcium carbonate D600, and the control group [...]
Aim To study the effect of tumor suppressor gene let-7b in breast cancer metastasis to lung, and to investigate the possible molecular mechanismsMethods The expression of let-7b was enforced and inhibited in vitro to detect the efficiency of cell migration and invasion in MDA-MB-231. Confirming the predicted targeting genes involved in possible regulation pathway. Injecting [...]
Objective Breast cancer is one of the most common female cancers, which is a serious threat to women. Recently, it has increased quickly, especially in some economically developed regions and cities of China. In such regions, the incidence rate of breast cancer ranks as the first female malignancy. The incidence and development of breast cancer [...]
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