Background:Tamoxifen (TAM) is a kind of selective estrogen receptor modulator, which exhibit tissue-specific estrogen agonist and antagonist effects. In 1977 by the United States Food and Drugs Authority approved for treatment of women who have breast cancer. It is found that the TAM can contain women estrogen receptors-positive breast cancer. Now TAM as pre-menopausal and [...]
BackgroundBreast cancer has became one of the major malignant diseases which threaten women’health seriously in the worldwild. Since 1980s, the incidence of breast cancer has showed an upward trend with annual increasing rate of 2%～3% in the world. This phenomenon is worse especially in the developing countries than the developed countries. Data has shown that [...]
BackgroundBreast cancer is the most frequently diagnosed cancer among women, the attack rate of it is the first place of all women cancer in developed countries in Europe and American, and only in American, breast cancer patients accounts for about 30 percent of all diagnosed cancer women. Although china belongs to lower incidence of breast [...]
Background:The biological targeted therapy for producing and molecular mechanisms of breast cancer is of high specificity and relatively low toxicity, and is currently one hotspot in the field of treatment for the breast cancer. Lapatintib is in the role of type 1 and type 2 Epidermal Growth Factor Receptor (EGFR/ErbB, a kind of tyrosine kinase [...]
BackgroundBreast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females, accounting for 23% of the total cancer cases and 14% of the cancer deaths, comprising 17% of the total new cancer cases and 23% of the total cancer deaths. Breast cancer is now also the leading cause of [...]
[Objective and significance]Breast cancer is the most commonly found carcinoma of female breasts, and also one of the most common malignant tumor in women, whose incidence and mortality has been increasing in recent years, ranking the top of the female carcinoma. Currently, the common treatments for breast cancer are the traditional surgical treatment, supplemented by [...]
OBJECTIVE:Today, breast cancer is the highest incidence of women malignant tumor. Body sex hormones influence tumor growth process,and chemotherapy drugs act on ovary making body homone secrete abnormalities, causing amenorrhoea in order to change the growth of tumor.This paper discuss the changing of sex hormones in chemotherapy to the effect of breast cancer.METHODS:Analyse 40 female [...]
PurposeWith the development of the knowledge about breast cancer, the view that breast cancer is an systemic disease has been widely accepted. Neoadjuvant chemotherapy has been a very important part of breast cancer systemic treatment. Neoadjuvant chemotherapy can downsize the tumors and increase the rate of breast-conserving surgery; control the micro-metastasis focus; provide information on [...]
Objective:Discuss about the features of the correlation of ultrasound elasticity with the expressions of estrogen receptor, progestron receptor, C-erbB-2 in breast cancer, and give a certain help in the endocrine therapy of breast cancer patients and the prognostic evaluation of it.Methods:Employ the SIEMENS Acuson Antares 5.0 color doppler ultrasound diagnostic instrument to examine. At first, [...]
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