Background Maintenance hemodialysis is the main renal replacement therapy for patients with end-stage kidney disease,In recent years,with hemodialysis equipment improvement and technological progress, hemodialysis patients significantly prolong their life. Then the complications and mental health problems are more outstanding, especially depression status. Depressed mood is the main characteristic of deprssion, its clinical manifestations can be [...]
BackgroundAtherosclerosis is the main underlying cause of ischemic vascular diseases and is predicted to become the leading cause of global mortality by 2050. Atherosclerotic plaques indicate the occurrence of ischemia events, and how to deal with it is a difficult task for clinical physician. Animal experimental studies have indicated that grape seed proanthocyanidin extract (GSPE) [...]
Objectives To investigate the levels of the serum pregnancy-associated plasma protein-A(PAPP-A)in the patients with ischemic cerebrovascular disease and its correlation with C-reactive protein (CRP)and matrix metalloproteinase-9 (MMP-9). To investigate the relationship between pregnancy-associated plasma protein A (PAPP-A) gene (exon 14 A/C (Tyr/Ser) (rs7020782)) polymorphism and ischemic cerebrovascular disease. To study the possible mechanism of PAPP-A [...]
BackgroundHealth in our country is seriously threatened by cancers and cardiovascular diseases which take up the first and second place in proportional mortality.the world health organization predicts that cardiovascular and cerebrovascular diseases will become the biggest cause of death. How to prevent and control cardiovascular and cerebrovascular diseases will be the chief mission of epidemiology. [...]
Objective:To observe the effects of Probucol combined with Atorvastatin and Atorvastatin on Atherosclerosis.Methods:18 New Zealand rabbits were divided into Control group (named A group, n=3) and High Fat Diet (HFD) group (named X group, n=15) randomly. HFD group was fed up with 2% cholesterol for 6 weeks. After 6 weeks, HFD group was divided into [...]
Objects:To investigate the anti-atherosclerosis effects and mechanism of Candesartan on experimental atherosclerosis rats.Methods:Male SD rats of ten-months were randomly divided into 5 groups:A(normal rats),B(atherosclerosis rats),C(atherosclerosis rats fed with candesartan 1 mg.kg-1.d-1), D(atherosclerosis rats fed with candesartan 5 mg.kg-1.d-1) and E(atherosclerosis rats fed with candesartan 10mg.kg-1.d-1). The rats of group B,C,D,E were fed with high lipid [...]
Atherosclerosis (atherosclerosis, AS) can lead to cardiovascular, cerebrovascular diseases, so it is serious disease threaten to human health. With the development of society and increasing competition of stress. It impact human health more and more. Therefore, the establishment of an ideal model of induction of oral tolerance on anti-atherosclerosis is significant. This study is based [...]
Objective To detect lipoprotein (a) (Lp(a)) and fibrinogen (FIB) levels in the different types of cerebral infarction, Lp(a) and FIB are compared between the various types of cerebral infarction. The relation between Lp(a)、FIB levels and different types of cerebral infarction is preliminary studied,These new ideas are provided for different types of cerebral infarction patients.Methods 121 [...]
BackgroundCoronary artery disease(CAD)is common disease, which has serious effects on the health of human beings, and their pathological basis is coronary artery atherosclerosis(CAAS),Carotid atherosclerosis(CAS)and coronary atherosclerosis have common pathology and risk factor, there is a certain correlation, Atherosclerosis (AS), most in the large and medium arteries, with the factors of age growth and bad living [...]
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