Objective:In order to find a better way to repair meniscal defects in avascular zone, MSCs are used as seed cells, BMP-2are used as cytokines,and autologous fibrin glue(FG) are used as matrix in experimental New Zealand rabbits models. In this study,passage and amplification of MSCs are not needed. By the induction of BMP-2, MSCs are converted [...]
Object:this study aims to research the effects of different activities on articular cartilage after anterior cruciate ligament injury in rabbits, Methods:Twenty four male New Zealand white rabbits (about three-months-old) were randomly selected one side of the knee joints to the anterior cruciate ligament transaction and divided into four groups averagely after operation:free feeding group, immobilization [...]
Background and objective:The early lesion of Ankylosing Spondylitis appears as sacroiliac joint cartilage anomaly. Sacroiliac joint is located in deep position with complex anatomical structure. Plain radiographs and CT can not display changes in articular cartilage. Although MRI can demonstrate, but general sequence imaging for cartilage is ineffective. However, articular cartilage is very thin, in [...]
ObjectiveTo esteblish experimental osteochondral tissue bank abided by AATB standards with slow-cooling gradient cryopreservation, observe cell viability and cell metabolism of preserved cartilage, and clinical application of osteochondral allgraft for three cases.MethodsThe human articular cartilage specimens came from the clinical brain death patients of Qianfoshan hospital,Shangdong province.The age of donors was controlled at 15-45 years [...]
ObjectiveTo esteblish experimental osteochondral tissue bank abided by AATB standards with slow-cooling gradient cryopreservation, observe cell viability and cell metabolism of preserved cartilage, and clinical application of osteochondral allgraft for three cases.MethodsThe human articular cartilage specimens came from the clinical brain death patients of Qianfoshan hospital,Shangdong province.The age of donors was controlled at 15-45 years [...]
Objective: In recent years, with the development of the tissue engineering, the use of tissue engineering treatment of articular cartilage defects has become a hotspot research. However, compared with those techniques, cartilage tissue engineering is a new strategy for cartilage repair emerging in recent years, and many studies about it are still ongoing. Because of [...]
BackgroundWith the aging of the human,high-energy trauma and other reasons,a variety of factors have led to increasing incidence of osteoarthritis.But current clinical treatment for osteoarthritis is lack of effective means.With the progress in basic science the research of cytokine treatment for osteoarthritis research has become popular.Transforming growth factorβ1 is a kind of multifunctional cytokines. It [...]
ObjectiveThe aim of this study was to compare the different water content of Static articular cartilage in the internal condyle of femur between the Moderate degree and severe degree clinical symptoms of osteoarthritis patients of the kidney–yang deficiency, and compare the relationship between the different water content, cartilage proteoglycan,viscoelasticity and osteoarthritis severity index (ISOA), to [...]
BackgroundArticular cartilage plays an important role in maintaining joint bearing and normal activity, cartilage disease are the important factor affect joint stability. Degenerative osteoarthritis (OA) is for clinical common diseases, OA is an important health concern, which leads elderly persons’disability of working and living, the pathogenesis is mainly articular cartilage degeneration and damage, it is [...]
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