Objective：The coal worker’s pneumoconiosis rabbits model was copied, and prove it’s feasibility andpracticability;To compare HRCT features of rabbits with Coal pneumoconiosis and it’s pathological results,and to explore their relationship.Methods：Forty rabbits were randomly divided into experimental group and control group .Twenty five rabbitsIntracheal injection of coal particles was applied 100mg／ml solution 2 ml／kg for experimental group [...]
Objective:Using rabbit skin liquefaction model to assess the effects of immunomodulators including recombinant human interferon-γ (rIFN-γ), recombinant human interleukin-2(rIL-2), dexamethasone and cyclophosphamide (CTX) on the development of tuberculosis (TB) lesions and tubercle bacillus load in liquefied caseum, establish essential method for therapeutic agent evaluation and study the mechanisms of tuberculosis liquefaction.Methods:Animals were divided into six [...]
OBJECTIVE: Sepsis represents a clinical syndrome resulting from the systemicinflammatory response to bacterial infection. The complicated proceeding ofpathophysiology in immune system of sepsis remains unclear, and it is difficult toadvance treatment of this important and frequent problem. The purpose of this studyis:(1) To establish a constant infectious abdominal peritonitis model in mice whichmimics the process [...]
Objective:In the clinical and animal model, and investigate the effect of Bushen Huoxue Shujin decoction on cervical intervertebral disc degeneration.Methods:Taking Of20cases with axial cervical pain, all patients were had been given Bushen Huoxue Shujin decoction a week, observe many clinical index such as TCM(Traditional Chinese Medicine) symptoms, Cervical spondylosis cervical functional score, VAS and SF-36health [...]
Objective To observe pathological change of parotid gland injury of radiated rats and establish an animal model by which study on the parotid gland radiation injuries.Methods Twenty adult Wistar rats were chosen as laboratory animals, which was Divided into two groups:Experimental group (15) and control group (5). The right parotid glands of experimental group were [...]
Objective: To clarify the effects of LPS on reparative dentin and dental pulp cells by observing the change of pulp cells and the formation of reparative dentin in periodontal animal model established by injecting LPS.Methods:1、Choice of the concentrations of LPS for periodontitis animal model Six rats periodontal models were induced by repeated injection of LPS [...]
Objective:Through the many factors made of composite model method, with the wide application of hot and humid card in the rat model and classic gouty arthritis model as a comparison, this paper explores the establishing of traditional Chinese medicine gouty arthritis damp and hot card in the rat model method, aims to develop gouty arthritis [...]
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