Objective:To make and study the rat model of steatohepatitis and hepatic fibrosis induced by high-fat diet, in the period of nonalcoholic hepatitis, using low molecular weight heparin to intervene, and in order to supply the model of hepatic fibrosis for further study of low molecular weight heparin.Methods:Model establishment phase:Male Sprague-Dawley rats (N=60) were randomly divided [...]
Objective:To observe the effects of estrogen on hindlimb movements recovery and the formation changes of neural cells of spinal cord injury in rats. To study the expression and the changes of GAP-43 in spinal cord of the animals. To preliminary study on the mechanism estrogen promotes maintenance of function in neurons after SCI.Methods:144 eight-week male [...]
Objective:Observe the bone growth of implant in inner core of bone harvest chamber which pre-installed artificial bone material and study the efficacy of the bone harvest chamber which repeatly implanted in mini-pigs pigs of Guizhou to observe the osteogenic potential of artificial bone material.Methods:In experimental group, filling osteoinduction of material in each inner core of [...]
Objective:①To establish an animal model of mice infected with Toxoplasma gondii, different dose of Toxoplasma gondii infected mice by intraperitoneal(i.p.) on the second trimester and select the appropriate dose.②Use of animal model infected with Toxoplasma gondii, investigate the concentration of placental lactogen,acetylcholine, epidermal growth factor and observed effect on material transport of placenta.③Use of animal [...]
Objectives:To study the hyperuricemic rat models induced by different Modeling methods and assess the effect of different concentration of soybean-based protein on uric acid and renal function in hyperuricemic rats.Materials and methods:Part 1:The Rats were divided into normal group and three model groups randomly. The standard feed was given as a positive control; the model [...]
The lack of proper animal models is still a major obstacle for AIDS research. Although nonhuman primate (NHP) is on the top list of consideration an ideal model in many aspects, the innate anti-retroviral restriction factors of NHP prevent the direct use of monkeys as animal models for HIV-1 infection. Recent studies have shown that [...]
Taihe black-bone silky fowl (TBSF) is an acknowledged breed of natural medical chicken in Chinese tradition, grows primarily in South China, Taihe, Jiangxi Province. As a traditional Chinese medicine, it can be used independently or in compound prescription, BSF has been proved to have the effects of nourishing liver and kidney, profiting vitality, reducing asthenia [...]
Part one The establishment of a rat model of acute rhinosinusitisObjective:To develop a rat model of acute rhinosinusitis by combination of Merocel sponge with Streptococcus pneumoniae.Methods:50 healthy SD rats were randomly divided into experimental group (40) and control group (10).The right noses of experimental group rats were inoculated with 0.1 milliliter Streptococcus pneumoniae and with [...]
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