Objective:To develop a better rat model of Hp-associated chronic atrophic gastritis.Methods:Sixty grade two male Wistar rats were divided randomly into 4 groups,15 rats per Groups, i.e. model group (Hp, sodium salicylate and ethanol group), control group A (normal control group), control group B (Hp group), control group C (sodium salicylate and ethanol group), control group [...]

Background:Malignant ascites is a manifestation of end stage events in cancers and associated with a poor prognosis. Except in breast and ovarian cancer, the median survival time is ranged from1to4months. Massive ascites can low down the quality of life of patients. The intent of therapy is palliative and improvement of quality of life. Intraperitoneal chemotherapy [...]

ObjectiveTo explore? the efficacy and safety of paclitaxel concurrent chemoradiotherapy for H22 hepatic carcinoma of mice, and observed the radiosensitizing effect of paclitaxel.Methods(1)?Recovered, Passaged and Cultured H22 cells. when the cells entered the logarithmic growth phase. they were respectively treated with paclitaxel of 0.006mg/l、0.06mg/l、0.6mg/l、6mg/l、60mg/L、600mg/l about 24h, and observed cells morphology by inverted microscope, then determined [...]

ObjectiveTo explore? the efficacy and safety of paclitaxel concurrent chemoradiotherapy for H22 hepatic carcinoma of mice, and observed the radiosensitizing effect of paclitaxel.Methods(1)?Recovered, Passaged and Cultured H22 cells. when the cells entered the logarithmic growth phase. they were respectively treated with paclitaxel of 0.006mg/l、0.06mg/l、0.6mg/l、6mg/l、60mg/L、600mg/l about 24h, and observed cells morphology by inverted microscope, then determined [...]

IntroductionLiver cancer is one of the most important diseases which are serious threats to people’s health and lives. Liver cancer has badly affected Chinese. According to the statistics, each year about 11 million people died of liver cancer in China, which accounts for about 45% of the world’s total. It often happens in middle-aged above, [...]

IntroductionLiver cancer is one of the most important diseases which are serious threats to people’s health and lives. Liver cancer has badly affected Chinese. According to the statistics, each year about 11 million people died of liver cancer in China, which accounts for about 45% of the world’s total. It often happens in middle-aged above, [...]

Objective:To establish and improve an animal model of mice colon cell cancer liver metastases in BALB/c mice, and provides stable platform for the study of liver metastasis mechanism and biological behaviour. Methods:CT26 murine colorectal cancer cell line selected by subcutaneous transfer made after the 3rd generation cell suspension and the CT26 cell suspension were inoculated [...]

Objective:This study uses nude mice as experimental models for cervical cancer, to investigate the inhibition and the mechanism of recombinant adeno-associated virus-endostatin(rAAV-ES)on the growth of transplanted tumor of nude mice,through detecting the expressions of Bcl-2, Bax and Caspase-3 in the transplanted tumor.Methods:Sixty mature, female nude mice of cervical cancer model were established by left anterior [...]

Objective: To study the pathological changes of venous valves in different time after the thrombosis of jugular vein of rabbits.Materials and methods: 1. To establish venous thrombosis model: New Zealand white rabbits were operated with the jugular veins ligatde on the right side. Thrombosis was confirmed by ultrasound one day after the ligation. 2. Experimental [...]

14. June 2012 · Comments Off · Categories: Clinical · Tags: , , , ,

Objective: To explore the differences of perfusion parameters with dynamic susceptibility contrast (DSC)-perfusion weighted imaging (PWI) between metastatic and benign lymph nodes, and to evaluate the early response of metastatic lymph node after radiotherapy in animal models.Methods: Twenty rabbits are divided randomly into two groups, the benign group(Group B)and malignant groups(Group M1 and M2). In [...]