Background: Ischemic heart disease is a serious cardiovascular disease, itthreatens human health, and the pathogenesis is closely linked with complex andmultiple systems. In cellular and molecular levels, ischemia and hypoxia could affectthe energy metabolism, metabolism, and even gene expressions of myocardial cells，all these changes simultaneously contribute to the development process of myocardialischemic disease. Traditional Chinese [...]
ObjectiveNourishing Qi and Eliminating Phlegm Treatment(NQEPT)” is the basic method of traditional chinese medicine(TCM) treating lung cancer in oncology department of the1st affiliated hospital of Guangzhou University of Chinese Medicine. The decoction named “YQCTF” have a major role in the treatment. It include Codonopsis, Poria, Pinellia etc. In the study of National Tenth Five Year [...]
Angiogenesis is closely related to tumor growth, invasion and metastasis. Tumorangiogenesis is a complex process, and MMPs play an essential role during the wholeprocess. MMP-26is a novel member of the family, the fact it can degradate fibrinimply that it is involed in tumor angiogenesis.Our team preliminary studies found that: In vitro, MMP-26can promote thehuman umbilical [...]
Objective:Isoliquiritigenin (ISL),a simple chalcone-type flavonoid, which is derived from licorice compounds and mainly present in roots of licorice and many other plants, foods, beverages and tobacco.It has been reported to possess a wide range of potent biological and pharmacological activities including anti-oxidative, anti-tumor, anti-aging, anti-inflammatory, anti-diabetic activities and so on. However, the angiogenic effects of [...]
Background and ObjectiveThe incidence of primary hepatic carcinoma is one of the highest among the malignant tumors. The mortality of primary hepatic carcinoma is located in the second place, just behind lung tumor in China. Thus, many researchers have been focused on the study of biological behavior, diagnosis and treatment of it. Rabbit VX2liver cancer [...]
Objective: Apelin-13has been shown to promote angiogenesis, however, it has notbeen tested whether Apelin-13also affect the bio-properties of microvascular endothelialcells (MVECs). Therefore, the present study is designed to investigate whether Apelin-13also exerts pro-angiogenesis effects on micro-endothelial cells isolated from the heart in ratand the role of AMPK signaling pathway in the process.Methods: Microvascular endothelial cells [...]
Purpose: Along with our country people’s living level of more and more high, clinicalmyocardial infarction increasing incidence, and myocardial infarction mortality rates, thetrend of increased year by year, adult is the main cause of death, serious harm to the health ofour people.This study traditional Chinese medicine and red: qi and activate blood circulation,dredging decoction of [...]
Aim:To observe the effect of salvianolic acid B (Sal B) on proliferation, migration and tube formation in vitro, to explore the protective effects of Sal B of myocardial angiogenesis and molecular mechanism rats with acute myocardial ischemia; to investigate the vasodilatory effect of Sal B and its mechanisms.Methods:1(1) MTT method was used to determine the [...]
Effects and molecular mechanisms of SePhen on angiogenesis in vitro of human umbilical vein endothelial cells (HUEVC) were investigated. The functional inhibition of selenium (Se) containing peptides derived from Se-enriched Spirulina platensis (SeSP-Ps) to angiotensin convert enzyme (ACE) was explored. The impacts of low, medium and high Se status on lipids up-taking of bone marrow [...]
Experimental study the effect of Yiqi Huoxue Formula on Angiogenesis and Expression of HGF in Ischemic Myocardium of Rats after Myocardial Infarction.Objective:Through the animal experiment, to observe the effects of Yiqi Huoxue Formula on angiogenesis and promote angiogenic factors HGF protein expression in ischemic myocardium in rats model after myocardial infarction, and to explore its [...]
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