BackgroundAcinetobacter baumannii infection has become clinically important pathogens of the21st century. As in recent years, the widespread use of antibiotics, bacterial resistance intensified, increasingly severe Acinetobacter baumannii has quick access to and dissemination of resistance, multi-drug resistant and extensively drug-resistant full-resistant abalone Man does not move the bacteria has shown a worldwide epidemic, the challenge [...]
Objective:To study the resistance,characterization of the class I integrongenes (intI1) and integrated gene cassettes in Acinetobacter baumanniiisolates from our hospital, analyze the relationship between class Iintegron and multidrug resistance.So as to provide the science basis forthe prevention,control and cure of the clinical infection and spread ofdrug resistant Acinetobacter baumannii.Method:We have Collected90strains of Bauman Acinetobacter randomlyFrom [...]
【Objective】We have applied SELEX （Systematic Evolution of Ligands by Exponentialenrichment）against the whole Acinetobacter Baumannii(A.Baumannii) as a complextarget to select single-stranded aptamers from a88nt single stranded DNA(ssDNA)random library.With epoxyethaneacrylic beads as screening medium, and the use ofdigoxinbiotin-alkaline phosphatase show color system, we tested and proved the highaffinity of aptmer to Acinetobacter Baumannii【Methods】1. Synthetize a88nt random oligonucleotides [...]
Part1Study of Mutant Prevention of Colistin combined with Levofloxacin against MDR-ABObjective:(1) To acquire MICs of ten antibiotics against MDR Acinetobacter baumannii isolated in recent years;(2) To select and class bacterial genotypes by PFGE;(3) Based on the theory of MSW, MPCs was to be measured and analysed of the strains;(4) To set up a method to [...]
Objective:To survey the drug resistance in Acinetobacter baumanniiclinical separations to 21 commonly used antimicrobial agents in the northeastof Si chuan ; To analyze the distribution and effects of seven 16 S rRNAmethylase genes, three aminoglycoside modifying enzymes genes and onekind of efflux pump gene in Acinetobacter baumannii with high-levelresistance to aminoglycosides or multiple resistance in [...]
Objective：To detect potential proteins which may play a key role in pathogenesis andearly diagnosis for Acinetobacter baumannii sepsis, we compared the protein profile ofneutrophils of na ve rats with that of rats infected with Acinetobacter baumannii.Methods：24adult male Wistar rats were divided into normal control group,Acinetobacter baumannii sepsis in6hour group and Acinetobacter baumannii sepsis in12hours group, [...]
Objective1. To investigate the actual reality about the popularity of the Non-fermenting Bacteria in ICU, analyze their antimicrobial resistance situation.2. To investigate the risk factors concerning about the complex infections and the disease prognosis in ICU, the correlation between the clinical experience and multi-drug resistant bacteria.3. To study theβ-lactamase resistance of multi-resistant Acinetobacter baumannii species [...]
Objective1. To investigate the actual reality about the popularity of the Non-fermenting Bacteria in ICU, analyze their antimicrobial resistance situation.2. To investigate the risk factors concerning about the complex infections and the disease prognosis in ICU, the correlation between the clinical experience and multi-drug resistant bacteria.3. To study theβ-lactamase resistance of multi-resistant Acinetobacter baumannii species [...]
ObjectivesTo descript the epidemiology of Acinetobacter baumannii in a surgical Intensive Care Unit (surgical ICU) of an university hospital; to analyze the risk factors of patients of Acinetobacter baumannii colonized; to analyze the relationships between STs by Multilocus Sqeuence Typing(MLST) scheme and drugresistance of Acinetobacter baumannii for the the clue of proper measurements of hospital [...]
Objective: Acinetobacter baumannii is an opportunistic pathogen .It is widely distributed in nature, the hospital environment and human skin surface, because of its strong ability to adapt to the external environment, Acinetobacter baumannii has become one of the important opportunistic pathogen in the hospital. Recent years, with excessive use of broad-spectrum antibiotics, Acinetobacter baumannii which [...]
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