[Objective] To observe the effect of Yuxianling Granula on the learning and memory, hippocampus MFS(mossy fiber sprouting) of KA induced-temporal lobe epilepsy in rat,and to study the impact of the related mechanisms.[Methods] By stereotactic apparatus, we locally injected KA in hippocampus of rats,and established model of temporal lobe epilepsy, Induced seizures. To ev-aluate the effct [...]
Background and ObjectiveChemotherapy is one of the classical treatment for malignant tumor in clinic. However, as the conduct of the treatment to the tumor or its different reactivity to chemotherapeutic drugs, many tumors develop resistance to chemotherapeutic drugs, sensitivity reduction, chemotherapy-induced bone marrow suppression, neurotoxicity, cardiovascular toxicity and other side effects, which not only seriously [...]
Aim:To investigate the clinicopathologic characteristics of Extracellular Matrix Metalloproteinase Inducer (EMMPRIN/CD147) and Vascular Endothelial Growth Factor (VEGF) expression in advanced renal cell carcinoma (RCC), and to evaluate the clinical significance of these two markers in the prognosis of advanced RCC.Background: Renal cell carcinoma (RCC) generally arises in the epithelium of the proximal tubule. Approximately 80% [...]
Objective:1.To study the relationgship of TAP2 and other correlative immunagenes、HPV16E6/18 E6with Kazakh’s esophageal cancer in Xinjiang; 2.To explore the role of the interaction of the TAP2 and other correlative immunity genes、HPV16E6/18E6 and the family history of EC in Kazakh’s.Method:1. A 1:2 matched case-control study was conducted with 90 cases of EC and 180 controls. All [...]
Objective To observe the expression of Smad4, MMP-9 and CD34 in colorectal carcinoma tissue and discuss the correlation between the expression of Smad4, MMP-9, MVD and the clinical pathology parameter, and their role in the occurrence and development of colorectal carcinoma. And then, we analyzed the correlativity of the Smad4 and MMP-9 and their effect [...]
[Objective]To study the expression of vascular endothelial growth factor receptor 2 (VEGFR-2) and platelet derived growth factorα(PDGFR-α) in benign pheochromocytomas, malignant pheochromocytomas and normal adrenomedullary tissue. To discuss the value in distinction between benign and malignant pheochromocytomas and the significance in the target therapy for malignant pheochromocytomas.[Methods]The expression of VEGFR-2 and PDGFR-αwas assessed in the [...]
Objective: To study the association of HLA-Cw*0602 allele with genetic susceptibility to psoriasis vulgar (PV) in Uighurs from Xinjiang.Methods: Using high-resolution polymerase chain reaction amplification with sequence specific primers(PCR-SSP),we detected the distribution frequencies of HLA-Cw*0602 allele among 200 patients with PV and 200 healthy controls from Xinjiang Uighurs,and analyzed the correlation of some carrying HLA-Cw*0602 [...]
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