Objectives The pathogenesis of Polycystic Ovary Syndrome （PCOS） is complex, both androgens and insulin resistance（IR） play a role in the onset of PCOS. The objective is to investigate the dose and time effects of androgens on the development of IR in PCOS and the molecular mechanisms by which testosterone induces insulin resistance in 3T3-L1 adipocytes [...]
Long gap injuries of peripheral nerve are currently treated through autologous peroneal nerve grafts or cable-like sutures of multi-strand grafted nerve fibers. However, these methods are limited due to graft-available, donor-site dysfunction or even morbidity. Meanwhile, fully recovering the functions of reconstructed tissue and organ grafts depend on the control and adjustment of peripheral nerves. [...]
Part 1 Study of the neuronal effect after nerve reconstruction for C5 rootresection in young rats ObjectiveTo illuminate the morphological basis of the neuronal effect of nerve reconstruction for obstetrical brachial plexus palsy through animal model, the retrograde death of dorsal root ganglion (DRG) sensory neurons and spinal cord motoneurons after earlier nerve reconstruction for [...]
With social development and economic globalization, more and more employees are experiencing job stress since organization reformed and new policy took into effect at recent years. Long-term excessive work pressure contributed to occupational stress, which is becoming a sever problem of public health. In 1994, the United Nations report had pointed out “World is becoming [...]
FKN/CX3CR1 plays a critical role in the process of trafficking white blood cells, inflammation and development of immune cells as well as allograft transplantation. In the past decades there are some progress in studying the structure and function of FKN/CX3CR1 based on the approach of biochemistry. However, few comprehensive investigations on the structure basis of [...]
It is a challenging medical problem to delay intrinsic muscle atrophy of hand resulted from peripheral motor nerve injury. Function loss of hand intrinsic muscle means the core function loss of upper extremity, which brings a lot of burden of mind and economy for patients, their family, and society. So, strengthen of basis research and [...]
Kawasaki disease (KD) is an acute vasculitis of childhood, manifested by fever and signs of mucocutaneous inflammation. Cardiovascular lesion, especially coronary artery lesion is main complication of KD. Coronary artery aneurysm or stenosis are the most critical complications. It’s the major death cause and has a long-term impact to the children suffered from KD. Therefore, [...]
Congenital heart disease with increased pulmonary blood flow commonly leads to the development of pulmonary hypertension and increased vascular reactivity. This abnormal postnatal hemodynamic state results in progressive structural and functional abnormalities of the pulmonary vascular bed. If uncorrected, these vascular changes result in obliteration of the pulmonary vascular bed and death secondary to severe [...]
Research PurposesSince performance assessment of health service has been advocated by world health organization (WHO) in the year 2000, the ideas and methods have been highly paid more attention by the countries around the world. As one of branches of health system, community health service (CHS) has being developed rapidly, a scientific evaluation on this [...]
CHAPTER ONETHE MECHANISM OF IRON INSULTS FROMERYTHROCYTE LYSIS AFTER RATINTRACEREBRAL HAEMORRHAGE AND THE ROLEOF DEFEROXAMINE INTERVENTIONObjective: The mechanism of the delayed brain damage after intracerebral hemorrhage(ICH) is complicated and not well understood. ICH results in an accumulation of iron in the brain that possibly contributes to brain delayed insults and severe neurological deficits post-hemorrhage. So [...]
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