Objective:1. Through the detection of obstructive sleep apnea hypopnea syndrome patients, type2diabetic patients, OSAHS with T2DM patients, healthy control group, we explore its role in the pathogenesis of patients with OSAHS with T2DM.2. Analysis plasma of apelin-12levels of CPAP therapy of the OSAHS its merger with T2DM.Method:1. All selected objects are given full-night polysomnography monitoring7hours. [...]
Object To study the expression of tumor necrosis factor-alpha (TNF-α) andinterleukin -1-alpha(IL-1α) in human middle ear cholesteatoma and granulation tissuefor discussing their roles in the otitis media development.Methods The specimen are selected from the First Clinical Medical College ofShanxi Medical University, department of Otolaryngology-Head and Neck , including35 cases from cholesteatoma specimens, 20 cases from [...]
Objective:the deafness gene chip is applyied to non-syndromic deafness patients for molecular etiology research. Provide theoretical guidance for the policy formulation and implementation of personalized prevention and treatment of deafness in the region.Method:The peripheral blood samples were collected and the DNA templates were extracted from the129non-syndromic deaf patients who are sporadic in schools for deaf-mutes [...]
Objective:The aquaporins (AQPs) are a familyof small integral plasma membrane proteins that transport water and small molecules such as glycerol, urea, and even ions inspecial cases, across the plasma membrane. They are conserved in bacteria,plants, and animals. To date,13members of the AQP family have been identified in mammals. The nasal mucosa vascular endothelial growth factor [...]
ObjectiveRetinal hemorrhage on visual impairment is serious,even can cause blindness.When theretinal is examined,it is commonly performed by systemic or ocular disease induced retinaldamage.Timely and accurate diagnosis and treatment of retinal hemorrhage is a kind of effectivemeasures to restored,improve visual function and prevent the disease continues to develop.Thispaper analyze the relevant risk factors and the prevention [...]
Objective To investigate the chronic nose – sinusitis after endoscopic sinussurgery and regular follow-up of the clinical significance of endoscopic sinussurgery for chronic nasal – sinusitis symptom improvement and quality of life impact.Method December 2009-September2010received in our department betweenendoscopic sinussurgery for chronic nasal – 120 patients with sinusitis, according tochronic nose – sinusitisdiagnosis and treatment [...]
Objective : To compare the separate and combined effects of active carbon absorption andepithelial curettage in corneal alkaliburned rabbits.Methods : 24 adult rabbits were randomly divided into 4 groups,6 rabbits each group.A: controlgroup.B: active carbon absorption group.C: epithelial curettage group.D: combined therapygroup.Then established the model of alkaliburned corneas in each right eye.After absorption andcurettage,same regular [...]
Objective Thyroid associated ophthalmopathy (Thyroid Associated Ophthalmopathy TAO)，the one of the most common orbital diseases in the adult，is a autoimmune disease.TAO is basedon the characteristics of the eye and per orbital tissue invasive disease and closely related togenetic factors. Peroxisome proliferator activated receptor gamma (PPAR gamma) is one of thedifferentiated transcriptive factors in the adipose [...]
BackgroudCholesteatoma is a common clinical disease, it has the continued growth of the tumor-likecapacity and the ability of bone destruction，so ,the cholesteatoma has been paid widen attentionby domestic and foreign experts. Although the causes of middle ear cholesteatoma and itsepithelial source there are still a lot of controversy, but the basic consensus is that the [...]
Objective:Airway inflammation is defined as a chronical inflammatory disease involving various inflammatory cells and inflammatory mediators. So far its management is not quite satisfactory partly because of its unveiled mechanism. Therefore it is very important to further investigate the pathogenesis of airway inflammation so as to develop a novel stragegy for this disease. Studies indicates [...]
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