Objictive: High incidence,high morbidity and mortality of cerebral infarction brought a heavy burden to the socity and the family, this study was to investigate the relationship between the serum level of matrixtalloproteinase-2, the volum size of infarction, degree of neurofunction impairment as well as prognosis in patients with acute cerebral infarction. We expect new intervention [...]
1. IntroductionMore than half of ischemic strokes are related to extra cranial athermanous disease in the developed world. In present clinical practice, selection for surgery or revascularization is based on the degree of luminal stenosis as measured by angiography such as ultrasound or magnetic resonance angiography (MRI). Carotid endarterectomy is well known to be beneficial [...]
Objective:To observe the differences of the number of hippocampal neurons、hippocampal volume、cell volume during kindling group in rats with temporal lobe epilepsy、non-kindling group and control group in rats, to explore the causal relationship of hippocampal sclerosis with Temporal lobe epilepsy.Methods:Status epilepticus was induced by a 20 min stimulation of the amygdala, Stimulated rats were monitored with [...]
Objective:Epilepsy is a chronic clinical syndrome characterized by a sudden, repeated and transient function of the central nervous system disorder caused by a excessive release of neurons. In recent years,people quest the pathogenesis of epilepsy from gene, molecular cytology and electrophysiology. The result is that potassium channels have relation with epilepsy. Potassium ion channels are [...]
BackgroudAlzheimer’s disease (AD) is one of the most common neurodegnerative disorders. The disease is defined by histopathologic features, especially the accumulation ofβ-amyloid peptides (Aβ) that forms senile plaques.β-amyloid peptides 1-42 (Aβ1-42) which are much more self-aggregated pron and daminging than other produced Aβpeptides are the major constituents of early senile plaques in AD brain. The [...]
Objective Neural tube defects is one of the most common birth defects, which comprises a series of defects such as anencephalia, encephalocoele, myeloschisis and so on. The development and differentiation of neural tube is a very complicated biological process. This process is regulated and affected by various teratogens, and one notable environmental teratogen is fetal [...]
Objective:To investigate the clinical features, MRI features and treatment of toxic encephalopathy induced by organic solvent. To further improve cognition of the clinical physician for toxic encephalopathy induced by organic solvent, thus reduce mistakes of diagnosis and treatment.Methods:The clinical features, MRI features and treatment of the 2 cases with chronic exposure to paint or shoe [...]
Objective:To explore the pathogenesis, clinical features and treatment strategies of hyperthyroidism combined with moyamoya disease.Methods:In this study, two cases of hyperthyroidism combined with moyamoya disease were described. At the meantime, we review the literature by searching the database of Chinenes scientific and technical journals、CBM、CNK、Pubmed from 1991 until now.Results:Coexistence of moyamoya disease and hyperthyroidism is very [...]
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