Objective: To observe the effect of PPAR gamma (peroxisome proliferator activated receptor )agonist pioglitazone pretreatment on myocardial ischemia reperfusion myocardial apoptosis andon the expression of GRP78 and Caspase-12 proteins in rats.so as to explore the the endoplasmicreticulun stress signaling pathways for pioglitazone in protection of m yocardium.Methods: male Wistar rats, the ordinary diet feeding. Weight [...]
ObjectiveObserve the different components of fine particulate matter (PM2.5) to rat cardiac hemodyna-mic effects and Myocardial tissue Ang II content. Further explore the might factors of the different components of PM2.5to rat cardiac function change.MethodsWistar rats randomly are divided into four groups;①Organic Extract Group,OG;②Water Soluble Extract Group, WG;③Mixing Extract Group,MG;④ontrol Group; every rat of each [...]
Objective To investigate the effect and mechanism of pretreatment with atorvastatin，pioglitazone，atorvastatin plus pioglitazone on myocardial ischemia reperfusion injury in ratsmodel.Methods 54 male wister rats were randomly divided into shame-operated group （n=6,normal saline 2ml/d）, I/R group （n=12, normal saline 2 ml/d）, atorvastatin group (n=12, atorvastatin 20mg kg-1d-1),pioglitazone group (n=12,pioglitazone 3mg kg-1d-1) and atorvastati+pioglitazone group (n=12, atorvastatin20mg [...]
BackgroundThe rise of cellular adoptive immunotherapy in the1880s gives the patients with tumor anew hope. Natural killer (NK) cells play a key role in the antitumor immune responses, plus thecapability of NK cells to kill tumor cells mainly depends on the synthesis of stimulatory andinhibitory signals on the cells surface, so NK cells become a [...]
Objective: To explore the capability and clinical value of Gemstone Spectral CT coronaryangiography in inspecting plaque in coronary artery.Methods: 56 patients who diagnosed coronary artery disease from Jun 2011 to November2011 in our hospital were divided into 2 groups according to clinical symptoms：stable anginapectoris group(SAP) and acute coronary syndrome group(ACS). All patients undergoneGemstone Spectral CT [...]
Objective To studay troponin additive to pulmonary embolism severityindex for the forecast value of severity in patients with actue pulmonary embolism.Methods we conducted a retrospecitive analysis of two hundred andforty-five patients admitted with PE confirmed by CT pulmonary angiogram orVentilation perfusion lung scanning in the NO 1 hosipital of shanxi medicaluniversity.According to the grouping of [...]
Background:Interstitial lung disease involve in the pulmonary mass,alveolar,and (or) thin bronchial diffuse lung disease. The clinical manifestations include unexplained chronic exertional dyspnea,with cough,lung burst and tone clubbing. Lung function expressed as a progressive restrictive ventilatory dysfunction and diffusion barriers.In recent years,the prevalence or incidence were an upward trend,and the prevalence is proportional with age The [...]
ObjectiveTo investigate the incentives of asthmatic exacerbation and provide a theoretical basis forthe prevention and treatment of asthma.Methods1.250cases of asthma acute attack patients from the department of the First HospitalAttached to Shanxi Medical University are the research object.Cases were divided into threegroups according to age. The factors to trigger asthma attacks were analyzed2.Allergens were tested [...]
Objective To investigate the effects of nucleoside (acid) analogues therapy on liverimprovement function in patients with hepatocirrhosis.Method Seventy-five patients with hepatocirrhosis were received Lamivudine 100 mg/d alone,or Lamivudine 100 mg/d combined with Adefovir Dipivoxil 10 mg/d, or Entecavir 0.5 mg/dalone for 104-week，then Child-Pugh score was calculated and compared between before andafter treatment. The rates of [...]
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