Background: Hemorrhagic-traumatic Shock is one of the leading criticalillnesses in the emergency department. HTS is a whole body blood, oxygendeficiency disease in which the body suffers after a severe blow. It has aninadequate tissue and organ perfusion as its main pathological, physiologychanges of systemic disease. If not timely or effectively treated, may lead toshock, infection [...]
Continuous renal replacement therapy is a common treatment in intensive care unit. The technique of CRRT has found increasing applicability in the treatment of patients with renal failure combined with cardiovascular instability, severe fluid overload, cerebral edema or hypercatabolism. With the development of the technology of CRRT, CRRT application category has extended from ARF to [...]
Objective Endothelial progenitor cells (EPCs) as a class of precursor cells, which can cycle, proliferate and differentiate into mature endothelial cells, not only involved in embryonic vascular development, but also played an important role in the adult organism angiogenesis in adult bone marrow and peripheral blood. Studies have shown that EPCs plays an important role [...]
Objective Endothelial progenitor cells (EPCs) as a class of precursor cells, which can cycle, proliferate and differentiate into mature endothelial cells, not only involved in embryonic vascular development, but also played an important role in the adult organism angiogenesis in adult bone marrow and peripheral blood. Studies have shown that EPCs plays an important role [...]
Objectives:The aim was to investigate the effects of different body temperature resuscitation on PPAR-γ, NF-κB, TNF-αand iNOS gene expression in the rats lung tissue during hemorrhagic shock.Methods:60 adult female Wistar rats were randomly assigned to three groups(n=20): control group(sham), normalthermia group(NR) and hypothermia group(HR). Rats in the control group underwent the surgical procedure but were [...]
Objective: This study was designed to evaluate the effects of the ATP-sensitive potassium-channel (KATP) inhibitor glibenclamide on acute lung injury （ALI） in a rat model of hemorrhagic shock.Methods:1.Rat model of controlled hemorrhagic shock: Adult female SPF Wistar rats, weighing 300±30g, were anesthetized with 10%chloral hydrate（3ml/kg） injected intraperitoneally.Catheters（PE-50） were inserted in both the left and right [...]
Objective: To observe the intervention of Smecta, Polymyxin B, and Vitamin B6 (SPV) on the intestinal redox in rats with severe traumatic hemorrhagic shock by establishment of traumatic hemorrhagic shock model of rats and measurement of serum changes of MDA, SOD, and to evaluate the possible mechanism of SPV on intestinal preservation in traumatic-hemorrhagic shock.Materials [...]
Objective: To observe the intervention of Smecta, Polymyxin B, and Vitamin B6 (SPV) on the intestinal redox in rats with severe traumatic hemorrhagic shock by establishment of traumatic hemorrhagic shock model of rats and measurement of serum changes of MDA, SOD, and to evaluate the possible mechanism of SPV on intestinal preservation in traumatic-hemorrhagic shock.Materials [...]
Objective: To observe the intervention of Smecta, Polymyxin B, and Vitamin B6 (SPV) on the intestinal redox in rats with severe traumatic hemorrhagic shock by establishment of traumatic hemorrhagic shock model of rats and measurement of serum changes of MDA, SOD, and to evaluate the possible mechanism of SPV on intestinal preservation in traumatic-hemorrhagic shock.Materials [...]
Objective:Traumatic hemorrhagic shock is the main causes leading to death of casualties. The early fluid resuscitation in pre-hospital phrase is one of the main treatments to the severe traumatic uncontrolled hemorrhagic shock. The rat model with severe traumatic uncontrolled hemorrhagic shock was built by drawing blood and cutting tails to observe the effects of different [...]
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