Objective:To investigate the protective effect of Tempol on skin photoaging caused by UVB in hairless mice.Methods:Seventy-two hairless mice were divided into normal control group (Group A), UVB radiation control group (Group B). topical use of Tempol and radiated after an hour group (Group C), topical use of Tempol and radiated after two hours group (Group [...]
Objective We examined the level of VIP、IL-5 and histamine in the serum of CIU group and compared with normal control group in order to determine the relationship of neuropsychiatric factors in the pathogenesis of CIU. Methods 46 cases diagnosed CIU patients and 34 healthy volunteers randomly selected (November 2008～April 2009) in our clinic. ELISA method [...]
BackgroundThe most of chronic eczema are associated with type IVallergy, which is cell immunity mediated by T cell.So far,there few reports of eczema modles,and mass of them are transgenic mouse.Tacrolimus is topical immunomodulators classified as calcineurin inhibitors.They belong to this group of substances with a high capacity to inhibit T lymphocyte activation. Although they also [...]
Vitiligo is a relatively common, acquired pigmentary disorder characterized by areas of depigmented skin, The prevalence of the disease is 0.1%-2%, Without preference of gender. The pathogenesis of vitiligo remains unclear. There are four hypotheses, autoimmune, genetic neural and melanocyte self-destruction. Researches showed that, vitiligo always associate with autoimmune diseases which prompted studies on the [...]
The prevalence of Dermatitis medicamentosa-like of trichloroethylene (DMLT) in workers shows a rising trend year by year, which appears to be a serious occupational health issue. Little is known about its pathogenesis to date, currently, the view that ODMLT is similar to delayed hypersensitive reaction according to its clinical characteristics was accepted widely. TH1 (helper [...]
Objective:To identify the HLA-DQA1*0302、DQB1*0303 alleles associated with vitiligo in the Uygur nationality of Xinjiang region.Methods:(1) Collect the 0.5ml peripheral blood of every subject,using the DNA extract kit of of sangon biotech Co Ltd to extract peripheral blood DNA, then using 0.7% agarose gel electrophoresis check the DNA quality;(2)Polymerase chain reaction sequence-specific primer (PCR-SSP) was used [...]
Syphilis is a chronic systemic disease which is caused by Treponema pallidum (abbreviated as TP). Syphilis is classified as B class infectious diseases in”Law of the PRC on the Prevention and Treatment of Infectious Diseases”, and is also one of the key monitoring infectious diseases in the entry-exit inspection and Quarantine Bureau. In recent years, [...]
Background:Psoriasis is a chronic inflammatory skin disease caused by genetic and environmental factors. It is easy to relapse and usually has a long course which effects seriously on physical and mental health of patients. Its prevalence varies in different places of the world. Race, geographic location and environment may be associated with the incidence of [...]
Background:The mechanisms of vitiligo remain unclear.Recent studies showed that patients with vitiligo were liable to accompany with other autoimmune diseases,especially the autoimmune thyroid diseases.In view of the different influence of race and heredity,we aim to investigate the characteristics of autoimmune thyroid diseases in Chinese vitiligo patients.Objective:To investigate the serum thyroid autoantibodies and thyroid hormone levels [...]
Objective: Herpes zoster and postherpetic neuralgia is common in clinical . The investigates into the relevant factors and intervention methods will be significative to prevent and reduce the incidence of PHN.Methods: Retrospective analysis of 134 cases of patients with herpes zoster cases, of which 23 cases with postherpetic neuralgia and 111 cases without postherpetic neuralgia [...]
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