Objective:(1) To explore the expressions of β-defensin-2(HBD-2)、β-defensin-3(HBD-3)、 interferon-gamma (IFN-y) in the lesional skin of Psoriasis Vulgaris,non-lesional skin tissues and normal tissues, as well as in mild, moderate and severe groups.(2) Comparison the expression difference of HBD-2, HBD-3, IFN-y between different groups and analysis the correlation of HBD-2and IFN-y, HBD-3and IFN-y.Further discuss the significantce of HBD-2and [...]
Objective:The etiology and pathogenesis of psoriasis has not yet fully understood，but recentpapers highlight the role of dysregulated expression of antimicrobial peptides (AMPs) in thepathogenesis of psoriasis. Human defensins (HBD) is one of the important AMPs. Through theinvestigation of the expression of humanβ-defensin -2(HBD-2)、humanβ-defensin -3(HBD-3)and tumour necrosis factor-α(TNF-α) in the lesional and uninvolved skin of psoriasisvulgaris [...]
BackgroundIn recent years invasive fungal infections have increased obviously, Candida albicans accountsfor the first number of conditional pathogenic fungi isolated,however,there has been a hugeincreases in the frequency of non-albicans Candida krusei due to the use of antifungal agents.Candida albicans and Candida krusei have increased as a consequence of resistance to azoleantifungal agents.Therefore, researches on the [...]
Objective: under different conditions, put psoriasis lesional epidermis stem cells (EpidermalStem Cells, ESCs ) in vitro separation, purification, cultivation and identification, to compareand find optimal culture conditions. Preliminary study are made about biological characteristicsof psoriatic epidermal stem cells, to provide the in-depth study basis of psoriatic lesions.Methods: 37 case of the skin lesions of psoriasis [...]
Objective: The study was to investigate the expression of CXCR3and CCR4and to study thechanges of T cell subpopulation (CD4+, CD8+) to explore their role in the pathogenesis ofCondyloma Acuminatum(CA).Methods: Expression of CXCR3and CCR4receptor on peripheral blood lymphocytes from thepatients of CA and control groups were detected.The distribution of CXCR3and CCR4onCD4+and CD8+were also evaluated by FACS.Results: [...]
BACKGROUNDAcne is a chronic inflammatory disease of the pilosebaceous follicle, theincidence of acne is70to87percent. Genetic factors, unhealthy lifestyles,stress from social life and overuse of cosmetics have made severe acnemuch more incidence in recent years, approximately8to18percent.Acne can cause a series of clinical symptoms, such as comedones,papules, pustules, nodules, cysts and various degrees of scarring. Thepathogenesis is [...]
Acne is dermatology common disease, it’s also a chronic inflammatory skin disease involving the sebaceous hair follicles, occur in the seborrhea site, can be expressed as acne, pimples, pustules, nodules, cysts and scar lesions. Involving more in15to30-year-old young men and women.ObjectiveObservation in Western medicine combines with the clinical efficacy of the treatment of acne.MethodA prospective [...]
ObjectiveThe purpose of this investigation is to understand the epidemiological characteristics in Guangzhou area of condyloma acuminatum. Which focuses on the Constitutional Types of TCM and HPV types, in order to provide scientific basis and new thinking for prevention and treatment of CAMethodIn the clinical respect,176Patients are all from GuangDong Province Hospital Of Traditional Chinese [...]
Hello,My name is Jack,Ph.D. Supervisor, Welcome to My WebSite