Objective:to inquire into the hemodynamic changes in early and late onset severe pre-eclampsia fetus’ umbilical artery and middle cerebral artery flow, and the relationship with perinatal outcome.Methods:apply the Color Doppler into detecting37normal cases of pregnancy(gestation weeks are diameter more than34),31normal cases of pregnancy (28～34weeks of gestation),30cases of early onset severe pre-eclampsia and30cases of late onset [...]
Objective:To compare a five-visit antenatal care (ANC) model with specified goals with the standard model on pregnancy outcome.Method:170pregnant women lining antenatal examination in the second clinical medical school of shanxi medical university were randomly allocated to provide either the new model (88pregnant women) or the standard model currently in use (82pregnant women). Women enrolled in [...]
Objective：To investigate the different expression of T-bet and GATA3 in decidua basalis betweenpreeclampsia and normal pregnant women. To explore the role of T-bet and GATA3in the pathogenesis of preeclampsia and provide new ideas for the etiology of preeclampsia.Methods：The patients with preeclampsia and normot ensive of late pregnancy were selected as studygroup and control group. The [...]
Objectiver:To compare the expression levels of T-bet and GATA-3in pre-eclamptic patients and to explore their significance in pre-eclampisa.Methods In a case-control study,13mild pre-eclampsia patients and13severe pre-eclampsia (SPE) patients were selected as the research group and14normal pregnant women as the control group. The expression levels of T-bet and GATA-3in decidua of three groups were detected using [...]
ObjectiveTo discuss the influence of different concentrations of rhuIL-2 on the serum estrogen(E2),serum progesterone(P) levels and the P/E2ratio of mice in mid-gestation and to oberve thepregnancy outcomes.MethodsBALB/c mice were divided into one control group and three treatment groups with differentdosage of rhuIL-2. Pregnant mice were intraperitoneally injected by sterile water in controlgroup and rhuIL-2 in [...]
Objective: To investigate the role of CD4~+CD25~+Treg in unexplained recurrentspontaneous abortion.Methods: An immunological model of abortion was used, in which the mating combinationCBA/J DBA/2J represents the abortion group, using the combination CBA/J BALB/c as anormal pregnancy control. On 14thday of pregnancy, the females were sacrificed. We use FlowCytometry to analyze the percentage of CD4~+CD25~+Treg in [...]
Objective1.By understanding the impact of IL-10、TNF-αon rat placental lactogrn, to discuss the influence of Th1 / Th2 Type of cell factors in the role of placental lactogrn secretion.2.To investigate when pregnant mice serum TNF alpha level rises, how the pregnant miceserum levels of mice PL will change,if giving IL-10 to intervene.MethodsPut sexual maturity mice into [...]
Pregnant women in pregnancy refers to the state of the particular physiological crowd, not only to maintain their nutritional needs, it also ensures that fetal growth and breast, the womb and the development of the placenta, need, at the same time for delivery and postpartum lactation do nutrition reserves. Pregnancy nutrition pregnancy outcome and fetus [...]
Objective:To compare the expression levels of IFN-y(Thl-type cytokines)、 IL-4(Thl-type cytokines) and IFN-y/IL-4(Thl/Th2)in pre-eclamptic serum and to investigate their role in pre-eclampisa.Methods:In45normal pregnant women,40mild pre-eclampsia patients and50severe pre-eclampsia (SPE) patients, The expression levels of IFN-yand IL-4in the three groups were detected by enzyme linked immunoassay(ELISA).Results:(1) The expression level of IFN-yin the SPE group higher than normal [...]
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